• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用于小儿烧伤的局部抗菌剂。

Topical antimicrobial agents for pediatric burns.

作者信息

Cartotto Robert

机构信息

Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre, University of Toronto, Rm D 712, 2075 Bayview Avenue, Toronto, ON M4N 3M5 Canada.

出版信息

Burns Trauma. 2017 Oct 19;5:33. doi: 10.1186/s41038-017-0096-6. eCollection 2017.

DOI:10.1186/s41038-017-0096-6
PMID:29075650
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5648513/
Abstract

While topical antimicrobial agents are indicated for most if not all burn wounds, the choice of a topical agent must consider many factors such as the wound depth, anticipated time to healing, need for surgical intervention, and the known cytotoxicity of the agent. Especially relevant to the pediatric burn patient are the antimicrobial agent's properties related to causing pain or irritation and the required frequency of application and dressings. This article will discuss the general principles surrounding the use of topical antimicrobials on burn wounds and will review the most common agents currently in use.

摘要

虽然局部抗菌剂适用于大多数(如果不是全部)烧伤创面,但局部用药的选择必须考虑许多因素,如创面深度、预期愈合时间、是否需要手术干预以及该药物已知的细胞毒性。对于小儿烧伤患者而言,特别相关的是抗菌剂与引起疼痛或刺激相关的特性以及所需的用药频率和敷料更换频率。本文将讨论烧伤创面局部使用抗菌剂的一般原则,并综述目前常用的最常见药物。

相似文献

1
Topical antimicrobial agents for pediatric burns.用于小儿烧伤的局部抗菌剂。
Burns Trauma. 2017 Oct 19;5:33. doi: 10.1186/s41038-017-0096-6. eCollection 2017.
2
Topical antimicrobials in pediatric burn wound management.儿科烧伤创面处理中的局部抗菌药物
J Craniofac Surg. 2008 Jul;19(4):913-22. doi: 10.1097/SCS.0b013e318175b516.
3
Topical treatment of pediatric patients with burns: a practical guide.儿童烧伤患者的局部治疗:实用指南。
Am J Clin Dermatol. 2002;3(8):529-34. doi: 10.2165/00128071-200203080-00003.
4
Cytotoxicity testing of burn wound dressings: first results.烧伤创面敷料的细胞毒性测试:初步结果。
Cell Tissue Bank. 2017 Jun;18(2):143-151. doi: 10.1007/s10561-017-9621-x. Epub 2017 Apr 7.
5
A systematic review of silver-containing dressings and topical silver agents (used with dressings) for burn wounds.含银敷料和局部用银剂(与敷料一起使用)治疗烧伤创面的系统评价。
Burns. 2012 May;38(3):307-18. doi: 10.1016/j.burns.2011.09.020. Epub 2011 Oct 24.
6
Systematic reviews of wound care management: (3) antimicrobial agents for chronic wounds; (4) diabetic foot ulceration.伤口护理管理的系统评价:(3)慢性伤口的抗菌剂;(4)糖尿病足溃疡。
Health Technol Assess. 2000;4(21):1-237.
7
[Topical agents used in the treatment of burns].[用于烧伤治疗的局部用药]
Med Pregl. 2002 Mar-Apr;55(3-4):109-13. doi: 10.2298/mpns0204109m.
8
[Application of topical drugs in burn wound].[局部用药在烧伤创面的应用]
Zhonghua Shao Shang Za Zhi. 2008 Oct;24(5):346-8.
9
Topical antimicrobial agents for burn wounds.用于烧伤创面的局部抗菌剂。
Clin Plast Surg. 2009 Oct;36(4):597-606. doi: 10.1016/j.cps.2009.05.011.
10
Topical antimicrobial therapy for treating chronic wounds.局部抗菌治疗治疗慢性伤口。
Clin Infect Dis. 2009 Nov 15;49(10):1541-9. doi: 10.1086/644732.

引用本文的文献

1
Zinc Alginate Hydrogel-Coated Wound Dressings: Fabrication, Characterization, and Evaluation of Anti-Infective and In Vivo Performance.海藻酸锌水凝胶涂层伤口敷料:制备、表征以及抗感染和体内性能评估
Gels. 2025 Jun 1;11(6):427. doi: 10.3390/gels11060427.
2
Hydrogel Containing Biogenic Silver Nanoparticles and Essential Oil for Burn Wounds: Antimicrobial Efficacy Using Ex Vivo and In Vivo Methods Against Multidrug-Resistant Microorganisms.含生物源银纳米颗粒和精油的水凝胶用于烧伤创面:采用体外和体内方法对多重耐药微生物的抗菌效果
Pharmaceutics. 2025 Apr 10;17(4):503. doi: 10.3390/pharmaceutics17040503.
3
Predictive value of systemic immune inflammation index for infections caused by healthcare in pediatric patients hospitalized to the burn unit.全身免疫炎症指数对烧伤科住院小儿患者医院感染的预测价值
Sci Rep. 2025 Apr 25;15(1):14562. doi: 10.1038/s41598-025-98258-8.
4
Multifunctional silver nanoparticle embedded eri silk cocoon scaffolds against burn wounds-associated infection.多功能银纳米颗粒嵌入的 eri 丝茧支架对抗烧伤创面相关感染。
RSC Adv. 2024 Aug 23;14(37):26723-26737. doi: 10.1039/d4ra05029k. eCollection 2024 Aug 22.
5
Multidrug-Resistant Organisms: The Silent Plight of Burn Patients.多重耐药菌:烧伤患者的无声苦难。
J Burn Care Res. 2024 Aug 6;45(4):877-886. doi: 10.1093/jbcr/irae075.
6
Advancing burn wound treatment: exploring hydrogel as a transdermal drug delivery system.推进烧伤创面治疗:探索水凝胶作为经皮给药系统。
Drug Deliv. 2024 Dec;31(1):2300945. doi: 10.1080/10717544.2023.2300945. Epub 2024 Feb 16.
7
Lipophosphonoxins-A Novel Group of Broad Spectrum Antibacterial Compounds.脂磷毒素——一类新型广谱抗菌化合物
Pharmaceutics. 2023 Sep 28;15(10):2395. doi: 10.3390/pharmaceutics15102395.
8
Effects of argan spinosa oil in the treatment of diaper dermatitis in infants and toddlers: A quasi-experimental study.刺阿干树油治疗婴幼儿尿布皮炎的效果:一项准实验研究。
J Taibah Univ Med Sci. 2023 May 22;18(6):1288-1298. doi: 10.1016/j.jtumed.2023.05.008. eCollection 2023 Dec.
9
Acellular fish skin for wound healing.脱细胞鱼皮在创伤愈合中的应用。
Int Wound J. 2023 Sep;20(7):2924-2941. doi: 10.1111/iwj.14158. Epub 2023 Mar 16.
10
Retrospective Study from a Single Center on the Efficacy of Pulsed Lavage Following Excision of Burns ≥30% of the Total Body Surface Area in 63 Patients.回顾性研究:单中心 63 例烧伤总面积≥30%患者切痂术后脉冲灌洗疗效分析。
Med Sci Monit. 2022 Nov 9;28:e937697. doi: 10.12659/MSM.937697.

本文引用的文献

1
Expert Recommendations for the Use of Hypochlorous Solution: Science and Clinical Application.次氯酸溶液使用的专家建议:科学与临床应用
Ostomy Wound Manage. 2015 May;61(5):S2-S19.
2
Epidemiology and Outcome of Patients With Burns Treated With Cerium Nitrate Silversulfadiazine.硝酸铈磺胺嘧啶银治疗烧伤患者的流行病学及预后
J Burn Care Res. 2017 Jan/Feb;38(1):e432-e442. doi: 10.1097/BCR.0000000000000448.
3
The role of silver sulphadiazine in the conservative treatment of partial thickness burn wounds: A systematic review.磺胺嘧啶银在浅度烧伤创面保守治疗中的作用:一项系统评价。
Burns. 2016 Nov;42(7):1377-1386. doi: 10.1016/j.burns.2016.03.029. Epub 2016 Apr 26.
4
The Antibacterial Activity of Acetic Acid against Biofilm-Producing Pathogens of Relevance to Burns Patients.醋酸对烧伤患者相关生物膜形成病原体的抗菌活性。
PLoS One. 2015 Sep 9;10(9):e0136190. doi: 10.1371/journal.pone.0136190. eCollection 2015.
5
A Randomized Controlled Study of Silver-Based Burns Dressing in a Pediatric Emergency Department.一项关于银基烧伤敷料在儿科急诊科的随机对照研究。
J Burn Care Res. 2016 Jul-Aug;37(4):e340-7. doi: 10.1097/BCR.0000000000000273.
6
Silver in medicine: the basic science.医学中的银:基础科学
Burns. 2014 Dec;40 Suppl 1:S9-S18. doi: 10.1016/j.burns.2014.09.010.
7
Inpatient silver sulphadiazine versus outpatient nanocrystalline silver models of care for pediatric scald burns: A value analysis.住院患儿磺胺嘧啶银与门诊纳米晶银治疗小儿烫伤护理模式的价值分析
Plast Surg (Oakv). 2014 Summer;22(2):99-102.
8
A simple cost-saving measure: 2.5% mafenide acetate solution.一项简单的成本节约措施:2.5%醋酸磺胺米隆溶液。
J Burn Care Res. 2014 Jul-Aug;35(4):349-53. doi: 10.1097/BCR.0b013e3182a22715.
9
Antibiotic prophylaxis for preventing burn wound infection.预防烧伤创面感染的抗生素预防用药
Cochrane Database Syst Rev. 2013 Jun 6;2013(6):CD008738. doi: 10.1002/14651858.CD008738.pub2.
10
Dressings for superficial and partial thickness burns.用于浅度和部分深度烧伤的敷料。
Cochrane Database Syst Rev. 2013 Mar 28;2013(3):CD002106. doi: 10.1002/14651858.CD002106.pub4.