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伪装成皮肤淋巴瘤的多发性发疹性皮肤纤维瘤

Multiple Eruptive Dermatofibromas Masquerading as Cutaneous Lymphoma.

作者信息

Monteiro Rowan, Aithal Vijay, Tirumalae Rajalakshmi

机构信息

Department of Dermatology, St. John's Medical College and Hospital, Bengaluru, Karnataka, India.

Department of Pathology, St. John's Medical College and Hospital, Bengaluru, Karnataka, India.

出版信息

Indian J Dermatol. 2016 Sep-Oct;61(5):581. doi: 10.4103/0019-5154.190131.

Abstract

A 34-year-old male came with complaints of multiple firms to hard nontender, nonitchy nodules, measuring 2 cm × 2 cm to 1 cm × 1.5 cm, present predominantly over the lower limbs. This condition started 5 years back as a single nodule over the thigh but gradually increased in number and size with time to involve both lower limbs. A differential diagnosis of cutaneous lymphoma and dermatofibroma was considered. He underwent a biopsy and immunohistochemistry for the same which were consistent with hemosiderotic histiocytoma and positive for vimentin. The patient was advised surgical excision for the same. The occurrence of multiple dermatofibromas although rare has been reported in a few case reports; however, the occurrence of multiple dermatofibromas of the hemosiderotic variant has not been documented yet.

摘要

一名34岁男性因下肢出现多个坚实至坚硬、无压痛、无瘙痒的结节前来就诊,结节大小为2厘米×2厘米至1厘米×1.5厘米。这种情况始于5年前大腿上出现的单个结节,但随着时间推移,数量和大小逐渐增加,累及双下肢。考虑了皮肤淋巴瘤和皮肤纤维瘤的鉴别诊断。他为此接受了活检和免疫组织化学检查,结果与含铁血黄素沉着性组织细胞瘤一致,波形蛋白呈阳性。建议该患者进行手术切除。虽然有多发性皮肤纤维瘤的病例报告较少见,但含铁血黄素沉着变异型的多发性皮肤纤维瘤尚未见文献记载。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4912/5029260/e6be4322585d/IJD-61-581a-g001.jpg

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