肝脏再生中的免疫细胞。

College of Veterinary Medicine, Shaanxi Center of Stem Cells Engineering & Technology, Northwest A&F University, Yangling, Shaanxi, China.

Oncotarget. 2017 Jan 10;8(2):3628-3639. doi: 10.18632/oncotarget.12275.

After partial hepatectomy, hepatocytes proliferate to restore mass and function of the liver. Macrophages, natural killer (NK) cells, natural killer T (NKT) cells, dendritic cells (DC), eosinophils, gamma delta T (γδT) cells, and conventional T cells, as well as other subsets of the immune cells residing in the liver control liver regeneration, either through direct interactions with hepatocytes or indirectly by releasing inflammatory cytokines. Here, we review recent progress regarding the immune cells in the liver and their functions during liver regeneration.

部分肝切除术后，肝细胞增殖以恢复肝脏的质量和功能。巨噬细胞、自然杀伤（NK）细胞、自然杀伤T（NKT）细胞、树突状细胞（DC）、嗜酸性粒细胞、γδT细胞和传统T细胞，以及驻留在肝脏中的其他免疫细胞亚群，通过与肝细胞的直接相互作用或通过释放炎性细胞因子间接控制肝脏再生。在此，我们综述了关于肝脏中的免疫细胞及其在肝脏再生过程中的功能的最新进展。