Thamlikitkul V, Trakulsomboon S
J Med Assoc Thai. 1989 Jul;72 Suppl 2:29-32.
Efficacy of povidone iodine antiseptic, betadine and germidine, was tested against normal skin flora and four pathogenic bacteria namely S. aureus, S. epidermidis, E. coli and Pseudomonas aeruginosa by a new model. The study was performed on the volar surface of forearms of ten patients. First of all, the skin flora was cultured then 10(8) cu/ml of the tested organisms was applied by a cotton swab and left to dry for 1 minute before the culture was repeated. Betadine or germidine was applied over the area previously painted with the organism. The culture was taken 1 to 2 minutes thereafter. The results showed that this model was feasible and convenient. Betadine and germidine are efficacious against normal skin flora and pathogenic bacteria.
采用一种新模型测试了聚维酮碘防腐剂、碘伏和洁尔灭对正常皮肤菌群以及四种病原菌（金黄色葡萄球菌、表皮葡萄球菌、大肠杆菌和铜绿假单胞菌）的效果。该研究在10名患者前臂掌侧进行。首先，培养皮肤菌群，然后用棉签涂抹10(8) 菌落形成单位/毫升的受试微生物，晾干1分钟后再次进行培养。在先前涂抹过微生物的区域涂抹碘伏或洁尔灭。此后1至2分钟采集培养样本。结果表明该模型可行且方便。碘伏和洁尔灭对正常皮肤菌群和病原菌均有效。
