Nolan K F, Urquidi V, Emery V C, Bishop D H
NERC Institute of Virology, Oxford, U.K.
J Gen Virol. 1989 Aug;70 ( Pt 8):2201-7. doi: 10.1099/0022-1317-70-8-2201.
Viruses that are very closely related to each other at the genetic and gene product level can prove difficult to distinguish, although they may differ in phenotype (for example in their virulence or vector preferences). A chimeric genetic probe has been developed and tested to distinguish the S RNAs of two closely related bunyaviruses, snowshoe hare and La Crosse viruses. The technique is applicable to other RNA species of these two bunyaviruses.
在遗传和基因产物水平上彼此密切相关的病毒，尽管其表型可能有所不同（例如它们的毒力或载体偏好），但可能难以区分。现已开发并测试了一种嵌合基因探针，用于区分两种密切相关的布尼亚病毒——雪兔病毒和拉克罗斯病毒的S RNA。该技术适用于这两种布尼亚病毒的其他RNA种类。
