手持式共聚焦显微镜在皮肤癌诊断中的应用：与宽探头共聚焦显微镜相比的优势与局限性
Application of Handheld Confocal Microscopy for Skin Cancer Diagnosis: Advantages and Limitations Compared with the Wide-Probe Confocal.
作者信息
Que Syril Keena T, Grant-Kels Jane M, Rabinovitz Harold S, Oliviero Margaret, Scope Alon
机构信息
Department of Dermatology, University of Connecticut Health Center, 263 Farmington Avenue, MC 6231, Farmington, CT 06030-6231, USA.
Department of Dermatology, University of Connecticut Health Center, 263 Farmington Avenue, MC 6231, Farmington, CT 06030-6231, USA.
出版信息
Dermatol Clin. 2016 Oct;34(4):469-475. doi: 10.1016/j.det.2016.05.009.
The clinical diagnosis of tumors on the curved surfaces of the face, around the eyes, and on the mucosal surfaces can be difficult, while biopsies and excisions can have functional and aesthetic consequences. To avoid unnecessary surgery, clinicians have been aiming to attain accurate noninvasive diagnosis of lesions at these sites. However, acquisition of high-quality images with dermoscopy and with traditional wide-probe reflectance confocal microscopy (WP-RCM) have been hampered with technical difficulties. This article discusses the technical parameters of the handheld reflectance confocal microscope and discusses its advantages and limitations compared with the WP-RCM.
面部曲面、眼周以及黏膜表面肿瘤的临床诊断可能具有挑战性，而活检和切除术可能会带来功能和美学方面的影响。为避免不必要的手术，临床医生一直致力于实现对这些部位病变的准确无创诊断。然而，使用皮肤镜和传统宽探头反射式共聚焦显微镜（WP-RCM）获取高质量图像一直受到技术难题的阻碍。本文讨论了手持式反射式共聚焦显微镜的技术参数，并探讨了其与WP-RCM相比的优缺点。
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