• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

手持式共聚焦显微镜在皮肤癌诊断中的应用:与宽探头共聚焦显微镜相比的优势与局限性

Application of Handheld Confocal Microscopy for Skin Cancer Diagnosis: Advantages and Limitations Compared with the Wide-Probe Confocal.

作者信息

Que Syril Keena T, Grant-Kels Jane M, Rabinovitz Harold S, Oliviero Margaret, Scope Alon

机构信息

Department of Dermatology, University of Connecticut Health Center, 263 Farmington Avenue, MC 6231, Farmington, CT 06030-6231, USA.

Department of Dermatology, University of Connecticut Health Center, 263 Farmington Avenue, MC 6231, Farmington, CT 06030-6231, USA.

出版信息

Dermatol Clin. 2016 Oct;34(4):469-475. doi: 10.1016/j.det.2016.05.009.

DOI:10.1016/j.det.2016.05.009
PMID:27692452
Abstract

The clinical diagnosis of tumors on the curved surfaces of the face, around the eyes, and on the mucosal surfaces can be difficult, while biopsies and excisions can have functional and aesthetic consequences. To avoid unnecessary surgery, clinicians have been aiming to attain accurate noninvasive diagnosis of lesions at these sites. However, acquisition of high-quality images with dermoscopy and with traditional wide-probe reflectance confocal microscopy (WP-RCM) have been hampered with technical difficulties. This article discusses the technical parameters of the handheld reflectance confocal microscope and discusses its advantages and limitations compared with the WP-RCM.

摘要

面部曲面、眼周以及黏膜表面肿瘤的临床诊断可能具有挑战性,而活检和切除术可能会带来功能和美学方面的影响。为避免不必要的手术,临床医生一直致力于实现对这些部位病变的准确无创诊断。然而,使用皮肤镜和传统宽探头反射式共聚焦显微镜(WP-RCM)获取高质量图像一直受到技术难题的阻碍。本文讨论了手持式反射式共聚焦显微镜的技术参数,并探讨了其与WP-RCM相比的优缺点。

相似文献

1
Application of Handheld Confocal Microscopy for Skin Cancer Diagnosis: Advantages and Limitations Compared with the Wide-Probe Confocal.手持式共聚焦显微镜在皮肤癌诊断中的应用:与宽探头共聚焦显微镜相比的优势与局限性
Dermatol Clin. 2016 Oct;34(4):469-475. doi: 10.1016/j.det.2016.05.009.
2
Using Reflectance Confocal Microscopy in Skin Cancer Diagnosis.应用共聚焦激光扫描显微镜于皮肤癌诊断。
Dermatol Clin. 2017 Oct;35(4):457-464. doi: 10.1016/j.det.2017.06.007. Epub 2017 Aug 7.
3
Melanomas.黑色素瘤
Dermatol Clin. 2016 Oct;34(4):411-419. doi: 10.1016/j.det.2016.05.004.
4
In Vivo and Ex Vivo Confocal Microscopy for Dermatologic and Mohs Surgeons.用于皮肤科和莫氏外科手术医生的体内和体外共聚焦显微镜检查
Dermatol Clin. 2016 Oct;34(4):497-504. doi: 10.1016/j.det.2016.05.012.
5
Lentigo Maligna, Macules of the Face, and Lesions on Sun-Damaged Skin: Confocal Makes the Difference.恶性雀斑样痣、面部斑疹及日光损伤皮肤病变:共聚焦显微镜发挥重要作用。
Dermatol Clin. 2016 Oct;34(4):421-429. doi: 10.1016/j.det.2016.05.005.
6
The Role of Reflectance Confocal Microscopy in Clinical Trials for Tumor Monitoring.反射共聚焦显微镜在肿瘤监测临床试验中的作用。
Dermatol Clin. 2016 Oct;34(4):519-526. doi: 10.1016/j.det.2016.06.001.
7
The combination of dermoscopy and reflectance confocal microscopy increases the diagnostic confidence of amelanotic/hypomelanotic lentigo maligna.皮肤镜检查和反射共聚焦显微镜检查的联合应用提高了无色素/色素减退性恶性雀斑样痣的诊断可信度。
J Dermatol. 2024 May;51(5):714-718. doi: 10.1111/1346-8138.17075. Epub 2024 Jan 13.
8
Non-invasive diagnosis of pink basal cell carcinoma: how much can we rely on dermoscopy and reflectance confocal microscopy?粉红色基底细胞癌的非侵入性诊断:我们能在多大程度上依赖皮肤镜检查和反射式共聚焦显微镜检查?
Skin Res Technol. 2016 May;22(2):230-7. doi: 10.1111/srt.12254. Epub 2015 Sep 4.
9
In vivo and ex vivo confocal microscopy for the evaluation of surgical margins of melanoma.体内和体外共聚焦显微镜在评估黑素瘤手术切缘中的应用。
J Biophotonics. 2020 Nov;13(11):e202000179. doi: 10.1002/jbio.202000179. Epub 2020 Aug 13.
10
Basics of Confocal Microscopy and the Complexity of Diagnosing Skin Tumors: New Imaging Tools in Clinical Practice, Diagnostic Workflows, Cost-Estimate, and New Trends.共聚焦显微镜检查基础与皮肤肿瘤诊断的复杂性:临床实践中的新型成像工具、诊断流程、成本估算及新趋势
Dermatol Clin. 2016 Oct;34(4):367-375. doi: 10.1016/j.det.2016.05.001. Epub 2016 Jul 27.

引用本文的文献

1
A Systematic Review and Meta-Analysis of Ocular and Periocular Basal Cell Carcinoma with First-Time Description of Dermoscopic and Reflectance Confocal Microscopy Features of Caruncle Basal Cell Carcinoma.眼及眼周基底细胞癌的系统评价与荟萃分析,首次描述泪阜基底细胞癌的皮肤镜及反射式共聚焦显微镜特征
Diagnostics (Basel). 2025 May 14;15(10):1244. doi: 10.3390/diagnostics15101244.
2
In Vivo Reflectance Confocal Microscopy Applied to Acral Melanocytic Lesions: A Systematic Review of the Literature.体内反射共聚焦显微镜在肢端黑素细胞性病变中的应用:文献系统综述
Diagnostics (Basel). 2024 Sep 25;14(19):2134. doi: 10.3390/diagnostics14192134.
3
Mind the Gap: A Questionnaire on the Distance between Diagnostic Advances and Clinical Practice in Skin Cancer Treatment.
注意差距:皮肤癌治疗中诊断进展与临床实践之间差距的问卷调查。
Medicina (Kaunas). 2024 Jan 15;60(1):155. doi: 10.3390/medicina60010155.
4
Developments and Clinical Applications of Noninvasive Optical Technologies for Skin Cancer Diagnosis.用于皮肤癌诊断的非侵入性光学技术的发展与临床应用
J Skin Cancer. 2022 Nov 18;2022:9218847. doi: 10.1155/2022/9218847. eCollection 2022.
5
Skin cancer detection using non-invasive techniques.使用非侵入性技术进行皮肤癌检测。
RSC Adv. 2018 Aug 6;8(49):28095-28130. doi: 10.1039/c8ra04164d. eCollection 2018 Aug 2.
6
Malignant lesions of the ear.耳部恶性肿瘤。
Arch Dermatol Res. 2022 Nov;314(9):839-845. doi: 10.1007/s00403-021-02304-0. Epub 2021 Nov 18.
7
Deep Learning for Basal Cell Carcinoma Detection for Reflectance Confocal Microscopy.深度学习在反射共聚焦显微镜下基底细胞癌检测中的应用
J Invest Dermatol. 2022 Jan;142(1):97-103. doi: 10.1016/j.jid.2021.06.015. Epub 2021 Jul 13.
8
A Surgical Pen-Type Probe Design for Real-Time Optical Diagnosis of Tumor Status Using 5-Aminolevulinic Acid.一种用于使用5-氨基乙酰丙酸对肿瘤状态进行实时光学诊断的手术笔型探头设计
Diagnostics (Basel). 2021 Jun 1;11(6):1014. doi: 10.3390/diagnostics11061014.
9
Advances in the use of reflectance confocal microscopy in melanoma.反射共聚焦显微镜在黑色素瘤应用中的进展。
Melanoma Manag. 2018 May 10;5(1):MMT04. doi: 10.2217/mmt-2018-0001. eCollection 2018 Jun.
10
Updates on the Management of Non-Melanoma Skin Cancer (NMSC).非黑色素瘤皮肤癌(NMSC)管理的最新进展。
Healthcare (Basel). 2017 Nov 1;5(4):82. doi: 10.3390/healthcare5040082.