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葡萄牙的人体囊尾蚴病:早已消失还是仍然存在?

Human cysticercosis in Portugal: long gone or still contemporary?

作者信息

Vilhena M, Fonseca A G, Dias S, Marques DA Silva J, Torgal J

机构信息

Instituto de Ciências Agrárias e Ambientais Mediterrânicas (ICAAM), Universidade de Évora, Portugal.

European Network on Taeniosis/Cysticercosis, CYSTINET - COST Action TD1302.

出版信息

Epidemiol Infect. 2017 Jan;145(2):329-333. doi: 10.1017/S0950268816002284. Epub 2016 Oct 4.

Abstract

Cysticercosis, a leading cause of acquired epilepsy in developing countries, has been controlled or eradicated in industrialized countries. This paradigm has recently been challenged, with human neurocysticercosis (NCC) being increasingly diagnosed in these countries. In order to assess the NCC burden in Portugal, a retrospective study on NCC hospitalizations (2006-2013) was conducted based on the national database on hospital morbidity: 357 hospitalized cases were detected. NCC was most frequent in the following age groups: 20-64 years (n = 197, 55·2%) >64 years (n = 111, 31·1%), and <20 years (n = 49, 13·7%). In the Norte and Centro regions cases tended to be older than in the Lisboa and Vale do Tejo Region. The results raise concerns for imported and autochthonous disease, suggesting the Lisboa and Vale do Tejo Region, due to its higher frequency of cases at younger ages, as a priority for research and intervention, and further suggest that NCC should be under surveillance (notifiable). The National Observatory of Cysticercosis and Taeniasis has been established and will define NCC cases as well as monitoring and surveillance.

摘要

囊尾蚴病是发展中国家后天性癫痫的主要病因,在工业化国家已得到控制或根除。最近这种模式受到了挑战,在这些国家,人类神经囊尾蚴病(NCC)的诊断越来越多。为了评估葡萄牙的NCC负担,基于国家医院发病率数据库对NCC住院情况(2006 - 2013年)进行了一项回顾性研究:共检测到357例住院病例。NCC在以下年龄组中最为常见:20 - 64岁(n = 197,55.2%)>64岁(n = 111,31.1%),以及<20岁(n = 49,13.7%)。在北部和中部地区,病例往往比在里斯本和特茹河谷地区的年龄更大。这些结果引发了对输入性和本地疾病的担忧,表明里斯本和特茹河谷地区由于其较年轻年龄段病例的较高发生率,应作为研究和干预的重点,并且进一步表明NCC应受到监测(需报告)。国家囊尾蚴病和绦虫病观察站已经成立,将对NCC病例进行界定以及监测和监督。

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