Parker Michael T
Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Yale J Biol Med. 2016 Sep 30;89(3):339-351. eCollection 2016 Sep.
Recent advances in sequencing technologies have opened the door for the classification of the human virome. While taxonomic classification can be applied to the viruses identified in such studies, this gives no information as to the type of interaction the virus has with the host. As follow-up studies are performed to address these questions, the description of these virus-host interactions would be greatly enriched by applying a standard set of definitions that typify them. This paper describes a framework with which all members of the human virome can be classified based on principles of ecology. The scaffold not only enables categorization of the human virome, but can also inform research aimed at identifying novel virus-host interactions.
测序技术的最新进展为人类病毒组的分类打开了大门。虽然分类学分类可应用于此类研究中鉴定出的病毒，但这并未提供有关病毒与宿主相互作用类型的任何信息。随着后续研究的开展以解决这些问题，通过应用一套典型的标准定义来描述这些病毒-宿主相互作用，将极大地丰富相关内容。本文描述了一个框架，利用该框架可以根据生态学原理对人类病毒组的所有成员进行分类。该框架不仅能够对人类病毒组进行分类，还可为旨在识别新型病毒-宿主相互作用的研究提供信息。
