Passali Desiderio, Gabelli Giacomo, Passali Giulio Cesare, Magnato Roberto, Platzgummer Stefan, Salerni Lorenzo, Lo Cunsolo Salvatore, Joos Alexandra, Bellussi Luisa Maria
ENT Department, University of Siena, Siena, Italy.
ENT Department, Sacred Heart University, Roma, Italy.
Int J Otolaryngol. 2016;2016:2801913. doi: 10.1155/2016/2801913. Epub 2016 Sep 8.
Allergic rhinitis is a common nasal disorder with a high impact on quality of life, high social costs in therapies, and a natural development towards asthma. Pharmacological therapy is based on several genres of medications, of which intranasal corticosteroids are currently the most widespread. Thermal water treatment has traditionally been used as adjunctive treatment for chronic rhinitis and sinusitis. The present study was carried out to assess the clinical efficacy of nasal inhalation of radioactive oligomineral water vapours from the Merano hot spring and to compare it with the clinical efficacy of mometasone furoate nasal spray. A comparative prospective study was performed in 90 allergic patients treated at Merano hot springs: a group of 54 subjects treated with radioactive thermal oligomineral water and a control group of 36 subjects treated with mometasone nasal spray. Patients of both groups were assessed before and after treatment by Sino-Nasal Outcome Test questionnaire, active anterior rhinomanometry with flow and resistance monitoring, measurement of mucociliary transport time, and cytological examination of nasal brushing/scraping. The study showed that inhalation treatment with radioactive hydrofluoric thermal water for two weeks produces an objective clinical and cytological improvement in allergic patients, similar to that obtained with mometasone furoate nasal spray.
变应性鼻炎是一种常见的鼻部疾病,对生活质量有很大影响,治疗的社会成本高昂,且有自然发展为哮喘的趋势。药物治疗基于多种类型的药物,其中鼻用糖皮质激素目前应用最为广泛。传统上,温泉水疗法一直被用作慢性鼻炎和鼻窦炎的辅助治疗。本研究旨在评估吸入来自梅拉诺温泉的放射性低矿化度水蒸气的临床疗效,并将其与糠酸莫米松鼻喷雾剂的临床疗效进行比较。对在梅拉诺温泉接受治疗的90名变应性患者进行了一项前瞻性对照研究:一组54名受试者接受放射性低矿化度温泉水治疗,另一对照组36名受试者接受糠酸莫米松鼻喷雾剂治疗。两组患者在治疗前后均通过鼻-鼻窦结局测试问卷、带有流量和阻力监测的主动前鼻测压法、黏液纤毛转运时间测量以及鼻刷检/刮片细胞学检查进行评估。研究表明,对变应性患者进行为期两周的放射性氢氟酸温泉水吸入治疗可产生客观的临床和细胞学改善,类似于使用糠酸莫米松鼻喷雾剂所获得的效果。