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成年人糖尿病患病率的种族差异是由肥胖差异所解释的吗?

Are racial differences in the prevalence of diabetes in adults explained by differences in obesity?

作者信息

O'Brien T R, Flanders W D, Decoufle P, Boyle C A, DeStefano F, Teutsch S

机构信息

Division of Chronic Disease Control, Centers for Disease Control, Atlanta, GA 30333.

出版信息

JAMA. 1989 Sep 15;262(11):1485-8.

PMID:2769899
Abstract

To determine whether the higher prevalence of diabetes found among blacks in the United States is explained by racial differences in obesity, we examined the prevalence of diabetes adjusted for adiposity, education, and income in a cohort of US Army veterans from the Vietnam era. Among 12,558 white men and 1677 black men, aged 30 to 47 years, blacks were more likely than whites to have diagnosed diabetes (adjusted prevalence ratio, 1.9; 95% confidence interval, 1.3 to 2.7). Within every age, adiposity, and socioeconomic stratum, blacks had a higher prevalence of diagnosed diabetes than whites. In a subgroup of veterans for whom fasting serum glucose values were measured, blacks were more likely than whites to have fasting hyperglycemia (fasting serum glucose value greater than or equal to 7.8 mmol/L) (adjusted prevalence ratio, 5.7; 95% confidence interval, 2.7 to 12.0). These data provide evidence that the higher prevalence of diabetes found among blacks is not explained by differences in obesity.

摘要

为了确定美国黑人中较高的糖尿病患病率是否可由肥胖方面的种族差异来解释,我们在一组越南战争时期的美国退伍军人队列中,研究了根据肥胖、教育程度和收入进行调整后的糖尿病患病率。在12558名年龄在30至47岁之间的白人男性和1677名黑人男性中,黑人比白人更有可能被诊断出患有糖尿病(调整后的患病率比值为1.9;95%置信区间为1.3至2.7)。在每个年龄、肥胖程度和社会经济阶层中,黑人被诊断出患有糖尿病的患病率都高于白人。在一个测量了空腹血清葡萄糖值的退伍军人亚组中,黑人比白人更有可能出现空腹血糖过高(空腹血清葡萄糖值大于或等于7.8 mmol/L)(调整后的患病率比值为5.7;95%置信区间为2.7至12.0)。这些数据表明,黑人中较高的糖尿病患病率不能用肥胖差异来解释。

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