Ghanem Sassine, Zaarour Mazen, Ibrahim Uroosa, Saouma Samer, Liu Ying, Kong Fanyi, Atallah Jean Paul
Internal Medicine, Staten Island University Hospital.
Hematology and Oncology, Tulane University.
Cureus. 2016 Aug 23;8(8):e746. doi: 10.7759/cureus.746.
Actinomycosis is a rare, chronic granulomatous infection caused by gram-positive, anaerobic to microaerophilic branching filamentous bacteria. In the cervicofacial region, it usually presents as an enlarging neck mass. It remains a diagnostic challenge due to the fact that cultures show no growth in more than 50% of cases. We report a case of a 67-year-old patient known to have a neck mass secondary to lymphoma in which the neck mass persisted despite therapy. Upon evaluation, the diagnosis of culture-negative actinomycosis was based on histopathology findings, and the patient received antibiotic therapy. We will discuss the diagnosis and pathology of actinomycosis, attempting to explore the relationship between actinomycosis and lymphoid malignancy.
放线菌病是一种由革兰氏阳性、厌氧至微需氧的分支丝状细菌引起的罕见慢性肉芽肿性感染。在颈面部区域，它通常表现为颈部肿块增大。由于超过50%的病例培养无生长，它仍然是一个诊断难题。我们报告一例67岁患者，已知患有继发于淋巴瘤的颈部肿块，尽管接受了治疗，颈部肿块仍持续存在。经评估，基于组织病理学结果诊断为培养阴性放线菌病，患者接受了抗生素治疗。我们将讨论放线菌病的诊断和病理学，试图探讨放线菌病与淋巴恶性肿瘤之间的关系。
