Hukki J, Attila M, Haikala H, Castren M, Lähteenmäki T, Smitten K V, Waris T
Division of Plastic Surgery, Töölö Hospital, Helsinki, Finland.
Microsurgery. 1989;10(2):110-2. doi: 10.1002/micr.1920100207.
Supradiaphragmatic inferior vena cava was transplanted end-to-end into the abdominal aorta of 11-week-old rats of the same inbred strain and same litter using microvascular technique. The grafts were removed 3 days, 4, 8, 16, and 35 weeks postoperatively, and their noradrenaline (NA) content was estimated by high-performance liquid chromatography using electrochemical detection. The amount of NA was significantly lower (P less than .001) in all vein grafts as compared to nontransplanted vena cava. The substantial decrease of NA in the vein grafts throughout the observation period indicates a persistent denervation of the transplant.
采用微血管技术，将膈上腔静脉端端移植到同品系、同窝11周龄大鼠的腹主动脉中。术后3天、4周、8周、16周和35周取出移植物，采用电化学检测的高效液相色谱法估算其去甲肾上腺素（NA）含量。与未移植的腔静脉相比，所有静脉移植物中的NA含量均显著降低（P<0.001）。在整个观察期内静脉移植物中NA的大幅减少表明移植物持续去神经支配。
