神经元钙内流：是神话还是现实？
Neuronal SOCE: Myth or Reality?
机构信息
Duke-National University of Singapore Medical School, Program in Neuroscience and Behavioral Disorders, Singapore.
Duke-National University of Singapore Medical School, Program in Neuroscience and Behavioral Disorders, Singapore; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
出版信息
Trends Cell Biol. 2016 Dec;26(12):890-893. doi: 10.1016/j.tcb.2016.09.008. Epub 2016 Oct 6.
Store-operated Ca entry (SOCE) is the primary Ca influx pathway in non-excitable cells. Long thought to be absent in nerve cells, neuronal SOCE is gaining popularity. We argue here that the evidence for SOCE in neurons remains contentious, mostly because SOCE imaging assays are inadequate in these cells.
钙库操纵性钙内流（SOCE）是非兴奋细胞中主要的钙内流途径。长期以来，人们认为神经元中不存在 SOCE，但神经元 SOCE 正受到越来越多的关注。我们在此认为，神经元中存在 SOCE 的证据仍然存在争议，主要是因为这些细胞中的 SOCE 成像检测方法不够充分。
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