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Relevance of a Geriatric Assessment for Elderly Patients With Lung Cancer-A Systematic Review.老年评估对老年肺癌患者的相关性——一项系统综述
Clin Lung Cancer. 2016 Sep;17(5):341-349.e3. doi: 10.1016/j.cllc.2016.05.007. Epub 2016 Jun 2.
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Screening for predictors of adverse outcome in onco-geriatric surgical patients: A multicenter prospective cohort study.老年肿瘤手术患者不良结局预测因素的筛查:一项多中心前瞻性队列研究。
Eur J Surg Oncol. 2015 Jul;41(7):844-51. doi: 10.1016/j.ejso.2015.02.018. Epub 2015 Apr 13.
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Prehabilitation to enhance perioperative care.术前康复以加强围手术期护理。
Anesthesiol Clin. 2015 Mar;33(1):17-33. doi: 10.1016/j.anclin.2014.11.002. Epub 2015 Jan 9.
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Prehabilitation interventions for older adults: an integrative review.老年人的术前康复干预:一项综合综述。
West J Nurs Res. 2015 Jan;37(1):103-23. doi: 10.1177/0193945914551006. Epub 2014 Sep 25.
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Therapeutic interventions for frail elderly patients: part I. Published randomized trials.衰弱老年人患者的治疗干预措施:第一部分。已发表的随机试验。
Prog Cardiovasc Dis. 2014 Sep-Oct;57(2):134-43. doi: 10.1016/j.pcad.2014.07.004. Epub 2014 Jul 22.
6
Frailty is a predictor of short- and mid-term mortality after elective cardiac surgery independently of age.衰弱是择期心脏手术后短期和中期死亡率的一个预测指标,与年龄无关。
Interact Cardiovasc Thorac Surg. 2014 May;18(5):580-5. doi: 10.1093/icvts/ivu006. Epub 2014 Feb 3.
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Frailty indicators and functional status in older patients after colorectal cancer surgery.老年结直肠癌患者术后的衰弱指标与功能状态
J Geriatr Oncol. 2014 Jan;5(1):26-32. doi: 10.1016/j.jgo.2013.08.001. Epub 2013 Aug 30.
8
An elevation of resting metabolic rate with declining health in nonagenarians may be associated with decreased muscle mass and function in women and men, respectively.在 90 岁以上的老年人中,随着健康状况的下降,静息代谢率升高,这可能与女性和男性的肌肉量和功能下降分别相关。
J Gerontol A Biol Sci Med Sci. 2014 Jun;69(6):650-6. doi: 10.1093/gerona/glt150. Epub 2013 Oct 25.
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Geriatric assessment improves prediction of surgical outcomes in older adults undergoing pancreaticoduodenectomy: a prospective cohort study.老年综合评估可改善行胰十二指肠切除术老年患者的手术结局预测:一项前瞻性队列研究。
Ann Surg. 2014 May;259(5):960-5. doi: 10.1097/SLA.0000000000000226.
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Frailty as a predictor of morbidity and mortality in inpatient head and neck surgery.衰弱作为住院头颈部手术患者发病率和死亡率的预测因子。
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胸外科手术患者的衰弱筛查

Screening for Frailty in Thoracic Surgical Patients.

作者信息

Beckert Angela K, Huisingh-Scheetz Megan, Thompson Katherine, Celauro Amy D, Williams Jordan, Pachwicewicz Paul, Ferguson Mark K

机构信息

Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin.

Department of Medicine, The University of Chicago Medicine, Chicago, Illinois.

出版信息

Ann Thorac Surg. 2017 Mar;103(3):956-961. doi: 10.1016/j.athoracsur.2016.08.078. Epub 2016 Oct 6.

DOI:10.1016/j.athoracsur.2016.08.078
PMID:27720368
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5944327/
Abstract

BACKGROUND

The presence of frailty or prefrailty in older adults is a risk factor for postsurgical complications. The frailty phenotype can be improved through long-term resistance and aerobic training. It is unknown whether short-term preoperative interventions targeting frailty will help to mitigate surgical risk. The purpose of this study was to determine the proportion of frail and prefrail patients presenting to a thoracic surgical clinic who could benefit from a frailty reduction intervention.

METHODS

A prospective cohort study was performed at a single-site thoracic surgical clinic. Starting October 1, 2014, surgical candidates 60 years of age or older who consented to be screened were included. Patients were screened using an adapted version of Fried's phenotypic frailty criteria: weakness (grip strength), slow gait (15-foot walk), unintentional weight loss, self-reported exhaustion, and low self-reported physical activity (Physical Activity Scale for the Elderly). Prefrailty was identified when participants demonstrated one to two frailty characteristics; frailty was identified when participants demonstrated three to five frailty characteristics.

RESULTS

Of 180 eligible patients, 126 consented, and 125 completed screening. Thirty-nine participants (31%) were not frail, 71 (57%) were prefrail, and 15 (12%) were frail. Exhaustion was the most common frailty symptom (34%). Frailty prevalence did not significantly differ among men and women (men: 10%, women: 14%; p = 0.75).

CONCLUSIONS

We found a high proportion of prefrail and frail patients among patients deemed candidates for thoracic surgical procedures. This finding indicates that frailty may be underrecognized. Substantial numbers of patients may be considered for a presurgical frailty reduction intervention.

摘要

背景

老年人存在衰弱或衰弱前期是术后并发症的危险因素。衰弱表型可通过长期抗阻训练和有氧运动得到改善。针对衰弱的短期术前干预是否有助于降低手术风险尚不清楚。本研究的目的是确定在胸外科门诊就诊的衰弱和衰弱前期患者中,能够从衰弱减轻干预中获益的患者比例。

方法

在一家单中心胸外科门诊进行了一项前瞻性队列研究。从2014年10月1日起,纳入年龄60岁及以上且同意接受筛查的手术候选患者。采用改良版的弗里德衰弱表型标准对患者进行筛查:虚弱(握力)、步态缓慢(15英尺步行)、非故意体重减轻、自我报告的疲劳以及自我报告的低体力活动(老年人体力活动量表)。当参与者表现出一至两个衰弱特征时,确定为衰弱前期;当参与者表现出三至五个衰弱特征时,确定为衰弱。

结果

180例符合条件的患者中,126例同意参与,125例完成筛查。39名参与者(31%)无衰弱,71名(57%)为衰弱前期,15名(12%)为衰弱。疲劳是最常见的衰弱症状(34%)。衰弱患病率在男性和女性之间无显著差异(男性:10%,女性:14%;p = 0.75)。

结论

我们发现,在被视为胸外科手术候选患者中,衰弱前期和衰弱患者的比例较高。这一发现表明衰弱可能未得到充分认识。大量患者可能适合接受术前衰弱减轻干预。