Schütte Kerstin, Balbisi Fathi, Malfertheiner Peter
Department of Internal Medicine and Gastroenterology, Niels-Stensen-Kliniken, Marienhospital Osnabrück, Osnabrück, Germany.
Department of Gastroenterology, Hepatology and Infectious Diseases, Otto von Guericke University of Magdeburg, Magdeburg, Germany.
Gastrointest Tumors. 2016 Sep;3(1):37-43. doi: 10.1159/000446680. Epub 2016 Aug 18.
The epidemiology of hepatocellular carcinoma (HCC) has significantly changed throughout the past decade and will continue to do so in the future as a consequence of effective primary prevention and treatment of virus-related liver diseases. However, other risk factors for HCC are constantly on the rise, including alcoholic liver disease and nonalcoholic fatty liver disease. The knowledge on these and further risk factors associated with an increased risk of HCC provide the opportunity and chance for the development and implementation of successful preventive strategies to decrease the worldwide burden of HCC. This mini-review gives a short overview on current strategies in primary, secondary, and tertiary prevention of HCC.
在过去十年中，肝细胞癌（HCC）的流行病学已发生显著变化，并且由于对病毒相关肝病的有效一级预防和治疗，未来还将继续变化。然而，HCC的其他风险因素却在不断增加，包括酒精性肝病和非酒精性脂肪性肝病。对这些以及与HCC风险增加相关的其他风险因素的了解，为制定和实施成功的预防策略提供了机遇，以减轻全球范围内HCC的负担。本小型综述简要概述了HCC一级、二级和三级预防的当前策略。
