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[败血梭状芽孢杆菌与结肠癌]

[Clostridium septicum and colonic cancer].

作者信息

Kurtzhals J A, Prag J, Terp J

出版信息

Ugeskr Laeger. 1989 Jul 17;151(29):1874-6.

PMID:2773100
Abstract

During the period 1980-1987, Clostridium septicum was identified at Statens Seruminstitut, from anaerobic blood cultures in six patients. Five of the patients had cancer of the colon or rectum (c. coli) and one had cancer of the ovary. Correspondingly great incidence of solid tumours, particularly c. coli with C. septicum infection without preceding trauma or compromizing of immunity has been reported in the literature. Meticulous bacteriological identification should be undertaken on anaerobic culture as the finding of C. septicum in the blood should instigate investigation for c. coli or another form of solid tumour if no other explanation for the infection is available.

摘要

在1980年至1987年期间,丹麦国家血清研究所从6名患者的厌氧血培养物中鉴定出败血梭菌。其中5名患者患有结肠癌或直肠癌(大肠杆菌),1名患有卵巢癌。文献报道,实体瘤,尤其是大肠杆菌合并败血梭菌感染且无先前创伤或免疫功能受损的情况,发病率相当高。对于厌氧培养应进行细致的细菌学鉴定,因为如果血液中发现败血梭菌,且对感染没有其他解释,就应促使对大肠杆菌或其他形式的实体瘤进行调查。

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