Nilsson O, Lindholm A, Christensson D
Swedish University of Agricultural Sciences, Uppsala.
Vet Parasitol. 1989 Jul 15;32(2-3):163-71. doi: 10.1016/0304-4017(89)90117-9.
A field evaluation of anthelmintics in 336 horses on 37 farms was conducted between February and May 1986 in Sweden. The herds, each comprising at least eight horses, had histories of grazing on permanent pastures and receiving regular treatments against parasites at least three times a year. Small strongyles were refractory to (pro)-benzimidazole drugs in all but one of 23 herds examined. There was an average reduction in egg output of approximately 60%, and approximately 30% of 205 horses examined were shedding less than 100 eggs g-1 7 days after treatment. There was great between-herd variation of both the faecal egg-count depression (6.4-90.4%) and drug efficacy (0.0-80.0%). The non-benzimidazole drugs under investigation were fully effective against mature small strongyles.
1986年2月至5月间，在瑞典对37个农场的336匹马进行了驱虫药的现场评估。这些马群每个至少有八匹马，有在永久牧场放牧且每年至少接受三次常规寄生虫治疗的历史。在所检查的23个马群中，除一个马群外，小型圆线虫对（前）苯并咪唑类药物耐药。处理后，卵产量平均下降约60%，在检查的205匹马中，约30%在处理7天后粪便中卵的排出量低于100个/克。粪便虫卵计数降低率（6.4 - 90.4%）和药物疗效（0.0 - 80.0%）在马群间差异很大。所研究的非苯并咪唑类药物对成熟小型圆线虫完全有效。
