Kal'nova N Iu
Vopr Med Khim. 1989 May-Jun;35(3):25-8.
Dynamics of antioxidative activity (AOA) of lipids was studied in tumors, in the tissues surrounding tumor and in blood plasma and erythrocytes of patients with mammary gland carcinoma after surgical and combined treatments. Intensity of lipid peroxidation was increased in blood plasma and erythrocytes of the treated patients within the later periods of the disease. AOA of the tumor lipids was elevated after the radiation treatment; at the same time, similar reaction to radiotherapy was detected in erythrocytes and the tissues surrounding tumor: a decrease in the AOA within the initial steps and elevation--during the later periods of the disease as compared with the activity in erythrocytes and tissues of treated patients. Qualitatively altered conditions of body functioning and its relationship with the tumor occurred apparently during the later periods of the disease.
研究了乳腺癌患者在手术和综合治疗后，肿瘤组织、肿瘤周围组织以及血浆和红细胞中脂质抗氧化活性（AOA）的动态变化。在疾病后期，接受治疗患者的血浆和红细胞中脂质过氧化强度增加。放疗后肿瘤脂质的AOA升高；同时，在红细胞和肿瘤周围组织中也检测到对放疗的类似反应：与接受治疗患者的红细胞和组织中的活性相比，疾病初期AOA降低，后期升高。在疾病后期，身体功能的定性改变及其与肿瘤的关系明显出现。
