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[体重、血脂、血皮质醇与大肠癌和乳腺癌患者的预后]

[Body weight, blood lipids, blood cortisol and prognosis of patients with cancer of the large intestine and breast].

作者信息

Kovalenko I G, Bershteĭn L M, Ostroumova M N, Dil'man V M

出版信息

Vopr Onkol. 1989;35(7):816-22.

PMID:2773397
Abstract

Survival was evaluated in 121 patients with breast cancer and 114 with colorectal tumors versus overweight, body surface, preoperative blood-cholesterol level, cholesterol fraction profile and blood-triglyceride and -11-hydroxycorticosteroid levels. Survival was assessed by actuarial method. In breast cancer patients, prognosis inversely correlated with overweight and preoperative blood-cholesterol level whereas in colorectal cancer--with preoperative blood-triglyceride level, and--in males--with those of 11-hydroxycorticosteroids. The prognostic significance of cancrophilia factors in cancer as well as differences in said significance for colorectal and breast tumors are discussed.

摘要

对121例乳腺癌患者和114例结肠直肠癌患者的生存情况进行了评估,评估指标包括超重、体表面积、术前血胆固醇水平、胆固醇组分分布以及血甘油三酯和11 - 羟基皮质类固醇水平。采用精算方法评估生存情况。在乳腺癌患者中,预后与超重和术前血胆固醇水平呈负相关,而在结肠直肠癌患者中,预后与术前血甘油三酯水平相关,在男性结肠直肠癌患者中,预后与11 - 羟基皮质类固醇水平相关。文中讨论了肿瘤嗜性因素在癌症中的预后意义以及结肠直肠癌和乳腺肿瘤在该意义上的差异。

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