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成人早衰症:沃纳综合征。

Adult Progeria: Werner Syndrome.

作者信息

Handargal Nagappa, Muralidharan Jananee, Sharma P Praveen, Narayanswamy M, Prabhu S, Priyashree R, Jagadeesha S G

机构信息

Professor.

Postgraduate Student.

出版信息

J Assoc Physicians India. 2016 Apr;64(4):93-94.

Abstract

Werner's syndrome is an adult premature aging syndrome of autosomal recessive inheritance affecting connective tissues throughout the body.1 The exact etiology remains obscure even though biochemical and connective tissue abnormalities have been postulated.2 The disease involves multiple systems of the body and may be associated with internal malignancy.3 We report a case of a 35 year old man who presented with uncontrolled diabetes and non-healing ulcers.

摘要

韦尔纳综合征是一种常染色体隐性遗传的成人早衰综合征,会影响全身的结缔组织。尽管已推测出存在生化和结缔组织异常,但其确切病因仍不清楚。该疾病累及身体的多个系统,可能与体内恶性肿瘤有关。我们报告一例35岁男性病例,该患者患有难以控制的糖尿病和不愈合溃疡。

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