Tan Lulu, Wong Kaichung, Connor David, Fakhim Babak, Behnia Masud, Parsi Kurosh
1 Dermatology, Phlebology and Fluid Mechanics Research Laboratory, St Vincent's Centre for Applied Medical Research, Australia.
2 School of Aerospace, Mechanical & Mechatronic Engineering, University of Sydney, Australia.
Phlebology. 2017 Aug;32(7):501-505. doi: 10.1177/0268355516671625. Epub 2016 Oct 12.
Objective To investigate the effect of agitation on foam temperature. Methods Sodium tetradecyl sulphate and polidocanol were used. Prior to foam generation, the sclerosant and all constituent equipment were cooled to 4-25℃ and compared with cooling the sclerosant only. Foam was generated using a modified Tessari method. During foam agitation, the temperature change was measured using a thermocouple for 120 s. Results Pre-cooling all the constituent equipment resulted in a cooler foam in comparison with only cooling the sclerosant. A starting temperature of 4℃ produced average foam temperatures of 12.5 and 13.2℃ for sodium tetradecyl sulphate and polidocanol, respectively. It was also found that only cooling the liquid sclerosant provided minimal cooling to the final foam temperature, with the temperature 20 and 20.5℃ for sodium tetradecyl sulphate and polidocanol, respectively. Conclusion The foam generation process has a noticeable impact on final foam temperature and needs to be taken into consideration when creating foam.
目的 研究搅拌对泡沫温度的影响。方法 使用十四烷基硫酸钠和聚多卡醇。在产生泡沫之前，将硬化剂和所有组成设备冷却至4 - 25℃，并与仅冷却硬化剂进行比较。使用改良的泰萨里方法产生泡沫。在泡沫搅拌过程中，使用热电偶测量120秒内的温度变化。结果 与仅冷却硬化剂相比，对所有组成设备进行预冷会使泡沫温度更低。起始温度为4℃时，十四烷基硫酸钠和聚多卡醇产生的泡沫平均温度分别为12.5℃和13.2℃。还发现仅冷却液体硬化剂对最终泡沫温度的冷却作用最小，十四烷基硫酸钠和聚多卡醇的温度分别为20℃和20.5℃。结论 泡沫产生过程对最终泡沫温度有显著影响，在制备泡沫时需要考虑这一点。
