Scott D J, Davies A H, Horrocks M
Bristol Royal Infirmary.
Ann R Coll Surg Engl. 1989 Jul;71(4):229-32.
Mortality rates after femoral embolectomy (FE) in patients with an acutely ischaemic leg vary from 20-40%. In the last 3 years we have adopted a policy of proceeding directly to femoral embolectomy in those patients with a strong clinical suspicion of an embolus. Where doubt exists about the diagnosis, arteriography is performed in combination with local streptokinase, balloon dilatation and/or reconstruction. In a prospective study between September 1984 and March 1987, 43 patients underwent femoral embolectomy with a limb salvage rate of 87%. The early mortality (within 30 days) was 16%, the late mortality was 26%, with a mean follow-up of 22 months. Of the seven patients who died within 30 days, one had a successful embolectomy but died from a cerebrovascular accident. The remaining six failed to improve clinically, all had poor backbleeding and no return of the peripheral pulses. None of these patients had an amputation. We recommend that femoral embolectomy be performed in those patients with a short history of ischaemia (less than 72 h), a risk factor suggesting an embolic source and no past history of intermittent claudication. If all three criteria are not met, arteriography should be performed with a view to fibrinolytic therapy or vascular reconstruction. In those patients who have had a failed embolectomy or where the circulation cannot be restored promptly, despite fibrinolytic therapy and/or distal reconstruction, early major amputation may be life-saving.
急性下肢缺血患者接受股动脉取栓术(FE)后的死亡率在20%至40%之间。在过去3年里,对于临床高度怀疑有栓子的患者,我们采取了直接进行股动脉取栓术的策略。当对诊断存在疑问时,则结合局部链激酶、球囊扩张和/或血管重建进行动脉造影。在1984年9月至1987年3月的一项前瞻性研究中,43例患者接受了股动脉取栓术,肢体挽救率为87%。早期死亡率(30天内)为16%,晚期死亡率为26%,平均随访22个月。在30天内死亡的7例患者中,1例取栓术成功,但死于脑血管意外。其余6例临床症状未改善,均存在回血不良且外周脉搏未恢复。这些患者均未进行截肢。我们建议,对于缺血病史短(少于72小时)、有提示栓子来源的危险因素且无间歇性跛行既往史的患者,应进行股动脉取栓术。如果这三个标准未全部满足,则应进行动脉造影,以便进行纤维蛋白溶解疗法或血管重建。对于取栓术失败的患者,或者尽管进行了纤维蛋白溶解疗法和/或远端血管重建但循环仍无法迅速恢复的患者,早期进行大截肢可能挽救生命。