Division of Biology and Biological Engineering, Howard Hughes Medical Institute, California Institute of Technology, Pasadena, California 91125, USA.
Nat Rev Neurosci. 2016 Oct 18;17(11):692-704. doi: 10.1038/nrn.2016.125.
Goal-directed social behaviours such as mating and fighting are associated with scalable and persistent internal states of emotion, motivation, arousal or drive. How those internal states are encoded and coupled to behavioural decision making and action selection is not clear. Recent studies in Drosophila melanogaster and mice have identified circuit nodes that have causal roles in the control of innate social behaviours. Remarkably, in both species, these relatively small groups of neurons can influence both aggression and mating, and also play a part in the encoding of internal states that promote these social behaviours. These similarities may be superficial and coincidental, or may reflect conserved or analogous neural circuit modules for the control of social behaviours in flies and mice.
目标导向的社交行为，如交配和战斗，与可扩展和持久的情绪、动机、唤醒或驱动力的内部状态有关。这些内部状态是如何被编码的，以及如何与行为决策和动作选择相联系的，目前还不清楚。最近在果蝇和老鼠身上的研究已经确定了在先天社交行为控制中起因果作用的回路节点。值得注意的是，在这两个物种中，这些相对较小的神经元群体可以影响攻击和交配行为，并且也在编码促进这些社交行为的内部状态中发挥作用。这些相似之处可能是表面的和偶然的，也可能反映了控制苍蝇和老鼠社交行为的保守或类似的神经回路模块。
