Hamad Shehab Ahmed, Naif Jandar S, Abdullah Mahdi A
Department of Oral and Maxillofacial Surgery, College of Dentistry, Hawler Medical University, Erbil, Kurdistan Region Iraq.
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Duhok University, Duhok, Kurdistan Region Iraq.
J Maxillofac Oral Surg. 2016 Sep;15(3):308-314. doi: 10.1007/s12663-015-0842-x. Epub 2015 Sep 25.
To evaluate the effect of low-level laser therapy on healing of extracted tooth socket of healthy rabbits.
The sample of this study was 20 male rabbits of 2-2.5 kg weight with age range of 8-12 months. Right and left lower first premolar teeth were extracted. The extraction sockets of lower right first premolar were irradiated with 0.9 W gallium-aluminum-arsenide (GaAlAs) diode laser for 5 min, immediately after extraction and then every 72 h for the next 12 days. The extraction socket of left side were not exposed to laser and served as a control. The animals were sacrificed after 7, 14, 30 and 45 days and the experimental and control sockets were removed from the harvested mandibles and prepared for haematoxylin and eosin staining and Masson's stain. The prepared slides were examined under light microscope for histological and histomorphometric examination.
The histological examination showed that diode laser-treated sockets demonstrated early formed new bone with faster maturation of primary bone to secondary bone as compared to non-treated control sockets. Histomorphometric analysis revealed a statistically significant increase in the density and volume of trabecular bone in laser-treated sockets than control sockets.
Diode laser application to tooth extraction socket has a positive effect on bone formation.
评估低强度激光疗法对健康兔拔牙创愈合的影响。
本研究样本为20只体重2 - 2.5千克、年龄8 - 12个月的雄性兔。拔除左右下颌第一前磨牙。右下第一前磨牙拔牙创在拔牙后立即用0.9瓦砷化镓铝（GaAlAs）二极管激光照射5分钟，随后每72小时照射一次，持续12天。左侧拔牙创不接受激光照射作为对照。在7、14、30和45天后处死动物，从收获的下颌骨中取出实验和对照拔牙创，准备进行苏木精和伊红染色以及马松染色。制备好的玻片在光学显微镜下进行组织学和组织形态计量学检查。
组织学检查显示，与未处理的对照拔牙创相比，二极管激光处理的拔牙创显示出早期形成的新骨，初级骨向次级骨的成熟更快。组织形态计量学分析显示，激光处理的拔牙创中骨小梁的密度和体积比对照拔牙创有统计学上的显著增加。
将二极管激光应用于拔牙创对骨形成有积极作用。
