口腔抗菌肽：类型及其在口腔中的作用。
Oral antimicrobial peptides: Types and role in the oral cavity.
作者信息
Khurshid Zohaib, Naseem Mustafa, Sheikh Zeeshan, Najeeb Shariq, Shahab Sana, Zafar Muhammad Sohail
机构信息
School of Materials and Metallurgy, University of Birmingham, United Kingdom.
Department of Community Dentistry and Preventive Dentistry, School of Dentistry, Ziauddin University, Pakistan.
出版信息
Saudi Pharm J. 2016 Sep;24(5):515-524. doi: 10.1016/j.jsps.2015.02.015. Epub 2015 Mar 6.
Antimicrobial peptides (AMPs) are a wide-ranging class of host-defense molecules that act early to contest against microbial invasion and challenge. These are small cationic peptides that play an important in the development of innate immunity. In the oral cavity, the AMPs are produced by the salivary glands and the oral epithelium and serve defensive purposes. The aim of this review was to discuss the types and functions of oral AMPs and their role in combating microorganisms and infections in the oral cavity.
抗菌肽（AMPs）是一类广泛的宿主防御分子，它们在早期发挥作用以对抗微生物入侵和挑战。这些是小的阳离子肽，在先天免疫的发展中起重要作用。在口腔中，抗菌肽由唾液腺和口腔上皮产生并发挥防御作用。本综述的目的是讨论口腔抗菌肽的类型和功能及其在对抗口腔微生物和感染中的作用。
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