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一例氯虫苯甲酰胺中毒合并急性胰腺炎后存活的病例。

A case of survival after chlorfenapyr intoxication with acute pancreatitis.

作者信息

Ku Jae Eun, Joo Young Seon, You Je Sung, Chung Sung Phil, Lee Hahn Shick

机构信息

Department of Emergency Medicine, Yonsei University College of Medicine, Seoul, Korea.

出版信息

Clin Exp Emerg Med. 2015 Mar 31;2(1):63-66. doi: 10.15441/ceem.15.004. eCollection 2015 Mar.

DOI:10.15441/ceem.15.004
PMID:27752575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5052853/
Abstract

Chlorfenapyr is a moderately hazardous insecticide. There have been previous reports of chlorfenapyr intoxication, but none have reported patient survival or an association with pancreatitis. A 61-year-old woman was brought to the emergency department with vomiting after ingesting 10 mL chlorfenapyr in a suicide attempt 1 hour before. The patient was treated with gastric lavage and activated charcoal, then transferred to the intensive care unit. Initial laboratory data were unremarkable except for elevated amylase/lipase levels (134/222 U/L), which were even higher 7 days later and remained elevated for 2 weeks. Abdominal computed tomography showed diffuse pancreatic swelling. The patient improved with conservative care and was discharged to home 19 days after admission. This is the first reported case of survival after chlorfenapyr intoxication. We recommend early aggressive management in the emergency department and close monitoring in the intensive care unit to detect and treat potentially fatal deterioration after chlorfenapyr intoxication.

摘要

溴虫腈是一种中度危险的杀虫剂。此前已有溴虫腈中毒的报告,但均未报告患者存活情况或与胰腺炎的关联。一名61岁女性在1小时前企图自杀摄入10毫升溴虫腈后因呕吐被送往急诊科。患者接受了洗胃和活性炭治疗,随后被转入重症监护病房。初始实验室数据无异常,仅淀粉酶/脂肪酶水平升高(134/222 U/L),7天后更高且持续升高2周。腹部计算机断层扫描显示胰腺弥漫性肿胀。患者经保守治疗后病情好转,入院19天后出院。这是首例报告的溴虫腈中毒后存活病例。我们建议在急诊科进行早期积极处理,并在重症监护病房密切监测,以发现和治疗溴虫腈中毒后可能致命的病情恶化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0abc/5052853/af02a2812c4e/ceem-15-004f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0abc/5052853/af02a2812c4e/ceem-15-004f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0abc/5052853/af02a2812c4e/ceem-15-004f1.jpg

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3
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