The Warren and Katharine Schlinger Laboratory for Chemistry and Chemical Engineering, Division of Chemistry and Chemical Engineering, California Institute of Technology , 1200 East California Boulevard, MC 101-20, Pasadena, California 91125, United States.
Org Lett. 2016 Nov 4;18(21):5449-5451. doi: 10.1021/acs.orglett.6b02722. Epub 2016 Oct 18.
A mild aerobic intramolecular aminoacetoxylation method for the synthesis of pyrrolidine and indoline derivatives was achieved using molecular oxygen as the oxidant. A catalytic NO species acts as an electron transfer mediator to access a high-valent palladium intermediate as the presumed active oxidant.
一种温和的有氧分子内氨基乙氧羰基化方法,用于合成吡咯烷和吲哚啉衍生物,使用分子氧作为氧化剂。催化的 NO 物种作为电子转移介质,以获得高价钯中间体作为假定的活性氧化剂。