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阿达木单抗治疗期间的科氏 kristinae 菌感染。

Kocuria kristinae infection during adalimumab treatment.

作者信息

Kolikonda Murali K, Jayakumar Priyanga, Sriramula Srividya, Lippmann Steven

机构信息

a Department of Neurology , University of Louisville School of Medicine , Louisville , KY , USA.

b Department of Medicine , University of Louisville School of Medicine , Louisville , KY , USA.

出版信息

Postgrad Med. 2017 Mar;129(2):296-298. doi: 10.1080/00325481.2017.1250606. Epub 2016 Oct 31.

DOI:10.1080/00325481.2017.1250606
PMID:27756166
Abstract

A common inhabitant of skin, the Kocuria kristinae of the Micrococcaceae family, has gained attention in recent years because it can induce pathology in humans. Reported is a Kocuria kristinae-caused abdominal abscess in a patient treated for rheumatoid arthritis with adalimumab. The tumor necrosis factor (TNF) inhibitor drugs are known to cause various bacterial, viral, and fungal infections. This is the first known case where an opportunistic infection with Kocuria has presented with an abdominal abscess in an immunocompromised individual who is on long term TNF inhibitors.

摘要

科氏葡萄球菌是微球菌科中一种常见的皮肤寄居菌,近年来因其可在人类中引发病变而受到关注。据报道,一名使用阿达木单抗治疗类风湿性关节炎的患者发生了由科氏葡萄球菌引起的腹部脓肿。已知肿瘤坏死因子(TNF)抑制剂药物会引发各种细菌、病毒和真菌感染。这是首例已知的在长期使用TNF抑制剂的免疫功能低下个体中,由科氏葡萄球菌引起的机会性感染表现为腹部脓肿的病例。

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