Chaubey Priyanka, Mohta Vandana, Mishra Manisha, Wagh Aniruddha, Sapre Satsheel
Department of Microbiology, Rashtrasant Tukdoji Regional Cancer Centre, Nagpur, Maharashtra, India.
Department of Head and Neck Oncology, Rashtrasant Tukdoji Regional Cancer Centre, Nagpur, Maharashtra, India.
Indian J Pathol Microbiol. 2023 Jan-Mar;66(1):14-18. doi: 10.4103/ijpm.ijpm_776_21.
Kocuria kristinae is a commensal organism, sometimes considered as a lab contaminant, but its repeated isolation from clinical samples in immunocompromised patients should raise red flags.
We confirmed the infection with re-isolation of the organism from the same site before starting treatment. For the identification of Kocuria kristinae we used IDGP cards on VITEK 2 compact system. Antibiotic susceptibility test was done manually following CLSI guidelines 2018 for Coagulase-negative staphylococci.
A total of 510 major head neck oncosurgeries were performed during the period of two years. Out of which 120 patients had skin and soft tissue infections. Out of these infected patients, 90 were culture positive and of these Kocuria kristinae were isolated in 12 patients. Resistance to penicillin and oxacillin is seen in all isolates.
Kocuria kristinae should not be ignored as a commensal flora or lab contaminant in immunocompromised hosts. Its Increase in resistance pattern is a matter of concern. It is an ignored opportunistic pathogen whose detailed sensitivity test should be developed to treat patients timely and effectively.
科氏克里斯蒂菌是一种共生菌，有时被视为实验室污染物，但在免疫功能低下患者的临床样本中反复分离出该菌应引起警惕。
在开始治疗前，我们通过从同一部位再次分离出该菌来确诊感染。对于科氏克里斯蒂菌的鉴定，我们在VITEK 2紧凑型系统上使用IDGP卡。按照2018年CLSI针对凝固酶阴性葡萄球菌的指南手动进行抗生素敏感性试验。
在两年期间共进行了510例主要的头颈肿瘤手术。其中120例患者发生皮肤和软组织感染。在这些感染患者中，90例培养呈阳性，其中12例分离出科氏克里斯蒂菌。所有分离株均对青霉素和苯唑西林耐药。
在免疫功能低下宿主中，科氏克里斯蒂菌作为共生菌群或实验室污染物不应被忽视。其耐药模式的增加令人担忧。它是一种被忽视的机会性病原体，应开展详细的敏感性试验以便及时有效地治疗患者。
