恶性淋巴瘤与职业暴露。
Malignant lymphomas and occupational exposures.
作者信息
Persson B, Dahlander A M, Fredriksson M, Brage H N, Ohlson C G, Axelson O
机构信息
Department of Occupational Medicine, University Hospital, Linköping, Sweden.
出版信息
Br J Ind Med. 1989 Aug;46(8):516-20. doi: 10.1136/oem.46.8.516.
The effects of potential risk factors for Hodgkin's disease (HD) and for non-Hodgkin lymphomas (NHL) were evaluated in a case-referent study encompassing 54 cases of HD, 106 cases of NHL, and 275 referents, all alive. Exposure information was obtained by questionnaires posted to the subjects. Crude rate ratios were increased for various occupational exposures including solvents, welding, wood preservatives, phenoxy acids, and fresh wood (sawmill workers, lumberjacks, paper pulp workers). After further analyses based on logistic regression occupational exposures to welding and creosote remained as significant risk factors for HD. For NHL, occupational exposures to solvents, phenoxy acids, and creosote but also work as carpenter or cabinet maker and contacts with pets (other than dogs, cats, and birds) were associated with significantly increased risks.
在一项病例对照研究中，对霍奇金淋巴瘤（HD）和非霍奇金淋巴瘤（NHL）潜在风险因素的影响进行了评估。该研究涵盖54例HD病例、106例NHL病例和275名对照者，所有研究对象均在世。通过向受试者发放问卷获取暴露信息。包括溶剂、焊接、木材防腐剂、苯氧基酸和新鲜木材（锯木厂工人、伐木工、纸浆工人）在内的各种职业暴露的粗率比有所增加。在基于逻辑回归的进一步分析后，焊接和杂酚油的职业暴露仍然是HD的显著风险因素。对于NHL，溶剂、苯氧基酸和杂酚油的职业暴露，以及从事木匠或橱柜制作工作和接触宠物（狗、猫和鸟以外的宠物）与风险显著增加有关。
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