Flodin U, Fredriksson M, Persson B, Axelson O
Department of Occupational Medicine, University Hospital, Linköping, Sweden.
Br J Ind Med. 1988 Jan;45(1):33-8. doi: 10.1136/oem.45.1.33.
The effect of potential risk factors for chronic lymphatic leukaemia was evaluated in a case-referent study encompassing 111 cases and 431 randomised referents, all alive. Information on exposure was obtained by questionnaires posted to the subjects. Crude rate ratios were increased for occupational exposure to solvents. DDT, engine exhausts, fresh wood (lumberjacks, paper pulp workers, and sawmill workers, for example) and also in farming. Further analysis of the material by means of the Miettinen confounder score technique reduced the number of rate ratios significantly exceeding unity to encompass only occupational exposure to engine exhaust, fresh wood, DDT, and contact with horses.
在一项病例对照研究中,对111例慢性淋巴细胞白血病患者和431名随机选取的对照者(均为在世者)的潜在风险因素进行了评估。通过向受试者发放问卷来获取暴露信息。职业性接触溶剂、滴滴涕、发动机废气、新鲜木材(例如伐木工人、纸浆工人和锯木厂工人)以及农业活动的粗率比均有所升高。采用米耶蒂宁混杂因素评分技术对资料进行进一步分析后,显著超过1的率比数量减少,仅包括职业性接触发动机废气、新鲜木材、滴滴涕以及与马匹接触。