使用《精神疾病诊断与统计手册》第四版（DSM-IV）的结构化临床访谈，比较日本血液透析患者与健康人群中重度抑郁症的患病率。

Prevalence of major depressive disorder among hemodialysis patients compared with healthy people in Japan using the Structured Clinical Interview for DSM-IV.

作者信息

Tomita Tetsu, Yasui-Furukori Norio, Sugawara Norio, Ogasawara Kohei, Katagai Koki, Saito Hisao, Sawada Kaori, Takahashi Ippei, Nakamura Kazuhiko

机构信息

Department of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, Japan.

Department of Neuropsychiatry, Graduate School of Medicine, Hirosaki University, Hirosaki, Japan; Aomori Prefectural Center for Mental Health and Welfare, Aomori, Japan.

出版信息

Neuropsychiatr Dis Treat. 2016 Sep 30;12:2503-2508. doi: 10.2147/NDT.S106817. eCollection 2016.

DOI:10.2147/NDT.S106817

PMID:27757034

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5053379/

Abstract

BACKGROUND

We investigated the prevalence of depression in hemodialysis (HD) patients using the Center for Epidemiologic Studies for Depression (CES-D) scale and the Structured Clinical Interview for the , Fourth Edition (SCID) and compared the rates with those of community dwelling people in Japan.

PATIENTS AND METHODS

A total of 99 patients undergoing HD were recruited. Blood sampling was performed no later than 2 weeks prior to assessment. As a reference group for SCID and CES-D evaluation, 404 age- and sex-matched healthy controls who had participated in the Iwaki Health Promotion Project were included in this study. The SCID and the CES-D scale were administered to all participants to diagnose their depression. Participants who met the criteria of a major depressive episode according to the SCID were classified as SCID depression and the participants whose CES-D score was 16 or higher were classified as CES-D depression.

RESULTS

Ninety-nine HD patients completed the evaluation and data collection. There were no significant differences in age, sex, or CES-D scores between HD patients and controls. There were 12 cases of SCID depression in HD patients and four cases in controls. There was a significant difference between HD patients and controls in the prevalence of SCID depression. There were no significant differences between the two groups with regard to demographic or clinical data. There were 19 HD patients and 24 controls who showed CES-D depression. There was no significant difference between HD patients and controls in the prevalence of CES-D depression. There was a significant difference in potassium level between the two groups, but there were no significant differences in any of the other items.

CONCLUSION

There were significantly more HD patients showing SCID depression than controls in the present study. In clinical settings, the SCID might be useful in surveying cases of depression detected by screening tools among HD patients.

摘要

背景

我们使用流行病学研究中心抑郁量表（CES-D）和《精神疾病诊断与统计手册》第四版结构化临床访谈（SCID）调查了血液透析（HD）患者中抑郁症的患病率，并将该患病率与日本社区居民的患病率进行了比较。

患者与方法

共招募了99例接受血液透析的患者。在评估前不迟于2周进行血液采样。作为SCID和CES-D评估的参照组，本研究纳入了404名参与岩城健康促进项目的年龄和性别匹配的健康对照者。对所有参与者进行SCID和CES-D量表评估以诊断其是否患有抑郁症。根据SCID符合重度抑郁发作标准的参与者被归类为SCID抑郁症患者，CES-D得分16分及以上的参与者被归类为CES-D抑郁症患者。

结果

99例HD患者完成了评估和数据收集。HD患者与对照者在年龄、性别或CES-D得分方面无显著差异。HD患者中有12例SCID抑郁症患者，对照者中有4例。HD患者与对照者在SCID抑郁症患病率方面存在显著差异。两组在人口统计学或临床数据方面无显著差异。有19例HD患者和24例对照者表现出CES-D抑郁症。HD患者与对照者在CES-D抑郁症患病率方面无显著差异。两组之间的钾水平存在显著差异，但在其他任何项目上均无显著差异。