Ghafouri Hamed Basir, Zare Morteza, Bazrafshan Azam, Modirian Ehsan, Mousavi Afkham, Abazarian Niloofar
MD, Assistant Professor of Emergency Medicine, Emergency Medicine Management Research Center, Iran University of Medical Sciences, Tehran, Iran.
MS, Nutrition Research Center, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Electron Physician. 2016 Aug 25;8(8):2707-2712. doi: 10.19082/2707. eCollection 2016 Aug.
Serum vitamin D concentration is a major contributing factor for increasing the risk of fall and fall-related injuries in older adults. However, when prescribed and supplemented for these populations, the outcomes are controversial, and in several cases no improvement has been reported in reducing the risk of recurrent falls. This study aimed to examine the association between serum vitamin D concentration and recurrent falls in Iranian older adults.
This cohort study was conducted in the emergency departments of two university hospitals. A cohort of 82 elderly participants aged over 60 and suffered from an unintentional episode of falling was evaluated six months after their first ED visit. A structured, self-administered checklist was developed to obtain the participants' demographic and clinical information. Participants also were asked about any recurrent fall experience during follow-up.
The mean (SD) age of the study population was 75 (8). Over half of the participants were male (57.3%). The mean (median) serum 25-hydroxyvitamin D (25 (OH)D) concentration was 38 (34) ng/ml. Mean serum 25(OH)D levels varied slightly between gender groups (p=0.450). An inverse but insignificant association was found between the age of participants and their serum 25(OH)D levels (r=-0.03, p=0.7). A small but insignificant association also was found between the mean serum 25(OH)D level and the number of recurrent falls in elderly patients irrespective of their age, gender, or physical activity groups (OR=1.008, p=0.992).
In contrast to previous studies, no significant association of serum 25(OH)D concentration was found with recurrent falls in Iranian older adults.
血清维生素D浓度是增加老年人跌倒及跌倒相关损伤风险的主要因素。然而,在为这些人群开具维生素D处方并进行补充时,结果存在争议,在某些情况下,并未报告在降低再次跌倒风险方面有改善。本研究旨在探讨伊朗老年人血清维生素D浓度与再次跌倒之间的关联。
本队列研究在两家大学医院的急诊科进行。对82名年龄超过60岁且有过一次意外跌倒事件的老年参与者在首次急诊就诊六个月后进行评估。制定了一份结构化的自填式清单以获取参与者的人口统计学和临床信息。还询问了参与者在随访期间是否有再次跌倒经历。
研究人群的平均(标准差)年龄为75岁(8岁)。超过一半的参与者为男性(57.3%)。血清25-羟维生素D(25(OH)D)的平均(中位数)浓度为38(34)ng/ml。不同性别组之间的血清25(OH)D平均水平略有差异(p = 0.450)。参与者年龄与其血清25(OH)D水平之间存在负相关但不显著(r = -0.03,p = 0.7)。无论年龄、性别或身体活动组如何,老年患者血清25(OH)D平均水平与再次跌倒次数之间也存在微弱但不显著的关联(OR = 1.008,p = 0.992)。
与先前的研究不同,在伊朗老年人中未发现血清25(OH)D浓度与再次跌倒之间存在显著关联。