经干扰素-γ预许可和未经预许可的冻存间充质基质细胞的功能取决于具体情况。
Function of Cryopreserved Mesenchymal Stromal Cells With and Without Interferon-γ Prelicensing is Context Dependent.
作者信息
Burand Anthony J, Gramlich Oliver W, Brown Alex J, Ankrum James A
机构信息
Department of Biomedical Engineering, University of Iowa, Iowa City, IA.
Fraternal Order of Eagles Diabetes Research Center, Pappajohn Biomedical Institute, University of Iowa, Iowa City, IA.
出版信息
Stem Cells. 2017 May;35(5):1437-1439. doi: 10.1002/stem.2528. Epub 2016 Nov 10.
Abstract
UNLABELLED
Tailoring MSCs to fit the disease. Fresh, cryopreserved and, prelicensed cryopreserved MSC are all being explored to treat numerous diseases, but all are not suitable to treat all conditions. injury. "*" denotes preferred therapeutic strategy when both fresh MSC and cryo-MSC have shown utility in treating the disease but one is more efficacious or logistically suitable.
ABBREVIATIONS
CLI, critical limb ischemia; GvHD. graft versus host disease; I/R, ischemia reperfusion (I/R); OI, osteogenesis imperfecta.
摘要
未标注
定制间充质干细胞以适应疾病。新鲜的、冷冻保存的以及预先许可的冷冻保存间充质干细胞都在被探索用于治疗多种疾病，但并非所有这些都适用于治疗所有病症。损伤。“*”表示当新鲜间充质干细胞和冷冻保存间充质干细胞在治疗该疾病中均显示出效用，但其中一种在疗效或后勤方面更合适时的首选治疗策略。
缩写
CLI，严重肢体缺血；GvHD，移植物抗宿主病；I/R，缺血再灌注（I/R）；OI，成骨不全。
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3
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Stem Cells Transl Med. 2015 Jun;4(6):615-24. doi: 10.5966/sctm.2014-0268. Epub 2015 Apr 29.
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