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急性泛发性脓疱性皮病(AGEP)——急性科医生需警惕的潜在陷阱。

Acute generalised exanthematous pustulosis (AGEP)-a potential pitfall for the acute physician.

作者信息

Cranga T A, Simpson M A, Featherstone P

出版信息

Acute Med. 2016;15(3):140-144.

PMID:27759749
Abstract

Acute generalised exanthematous pustulosis is a rare drug-induced dermatosis with an incidence of 1-5 cases per million cases per year, characterised by the appearance of hundreds of sterile pustules over erythematous and oedematous skin. Fever and neutrophilia are usually present. It has a rapid course and usually resolves following discontinuation of the precipitating drug or as a result of topical corticosteroid treatment. A patient with AGEP, who presented with generalized pustulosis lesions after the use of Flucloxacillin for cellulitis is described, along with the management and differential diagnosis of this condition.

摘要

急性泛发性脓疱病是一种罕见的药物性皮肤病,年发病率为百万分之一至五例,其特征是在红斑和水肿皮肤上出现数百个无菌脓疱。通常伴有发热和中性粒细胞增多。病程进展迅速,通常在停用诱发药物或经局部糖皮质激素治疗后消退。本文描述了一名在使用氟氯西林治疗蜂窝织炎后出现泛发性脓疱病皮损的急性泛发性脓疱病患者,并介绍了该病的治疗及鉴别诊断。

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Cephalexin-induced acute generalized exanthematous pustulosis.头孢氨苄诱发的急性泛发性脓疱性皮疹病
Dermatol Reports. 2018 Oct 1;10(2):7686. doi: 10.4081/dr.2018.7686.