在6年随访期间壁细胞和甲状腺抗体与胃黏膜状态及基础血清胃泌素水平的关系
Relation of parietal cell and thyroid antibodies to the state of gastric mucosa and basal serum gastrin levels during a 6-year follow up.
作者信息
Uibo R, Krohn K, Villako K, Tammur R, Tamm A
机构信息
Institute of General and Molecular Pathology, Tartu State University, Estonian SSR.
出版信息
Clin Exp Immunol. 1989 Aug;77(2):202-5.
Two groups of volunteers (199 in total, 149 of whom were a random sample of an urban population) were examined twice, with a 6-year interval, for the occurrence of parietal cell antibody (PCA) and thyroid microsomal antibodies (TMA). The antibody findings were compared with the antral and fundal gastric mucosal state, and with the fasting serum gastrin-17 level. During the study period, two new PCA and four new TMA cases appeared. There were no significant changes in the state of gastric antral/fundal mucosa in relation to PCA and/or TMA persistence or appearance, as compared with the gastric mucosa changes in the whole random population sample. However, a good correlation was observed between PCA and basal serum gastrin elevation.
两组志愿者（共199人，其中149人是城市人口的随机样本）接受了两次检查，间隔6年，检测壁细胞抗体（PCA）和甲状腺微粒体抗体（TMA）的出现情况。将抗体检测结果与胃窦和胃底黏膜状态以及空腹血清胃泌素-17水平进行比较。在研究期间，出现了2例新的PCA病例和4例新的TMA病例。与整个随机人群样本中的胃黏膜变化相比，胃窦/胃底黏膜状态与PCA和/或TMA的持续存在或出现并无显著变化。然而，观察到PCA与基础血清胃泌素升高之间存在良好的相关性。
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