Wang J J, Xue Y Y, Tang M
Key Laboratory of Environmental Medicine and Engineering, Ministry of Education, School of Public Health & Collaborative Innovation Center of Suzhou Nano Science and Technology, Southeast University, Jiangsu Key Laboratory for Biomaterials and Devices, Nanjing 210009, China.
Zhonghua Shao Shang Za Zhi. 2016 Oct 20;32(10):631-634. doi: 10.3760/cma.j.issn.1009-2587.2016.10.014.
With the rapid development of modern science and technology, the application of nanomaterial is ubiquitous in our daily life and medical field, in which the application related to nano-silver is more extensive. On one hand, it can make positive effects, such as anti-bacteria, anti-virus, anti-fungi, anti-parasitic infection and anti-tumor. In particular, its anti-bacterial activity in some acute or chronic treatment of infected wounds is more prominent. The application in diseases of gynecology, orthopedics, cardiovascular system, oral cavity, and ophthalmology is increasing. On the other hand, it can induce negative impacts and potential toxicity. It can be harmful to skin, gastrointestinal tract, respiratory tract, cardiovascular system, and so on. This article summarizes the antimicrobial application of nano-silver on treatment of diseases, its potential toxic effects on some organs or systems, and the possible toxic mechanism, as well as makes prospects of the research trends of nano-silver in future.
随着现代科学技术的飞速发展，纳米材料在我们的日常生活和医学领域中无处不在，其中与纳米银相关的应用更为广泛。一方面，它能产生积极作用，如抗菌、抗病毒、抗真菌、抗寄生虫感染和抗肿瘤。特别是其在一些急慢性感染伤口治疗中的抗菌活性更为突出。在妇科、骨科、心血管系统、口腔和眼科疾病中的应用也在增加。另一方面，它会产生负面影响和潜在毒性。它可能对皮肤、胃肠道、呼吸道、心血管系统等有害。本文总结了纳米银在疾病治疗中的抗菌应用、其对某些器官或系统的潜在毒性作用及可能的毒性机制，并对纳米银未来的研究趋势进行了展望。
