Xing Fu-Yan, Guan Lin-Lin, Li Yan-Long, Jia Chun-Juan
Department of Cardiology, DaQing Oil Field General Hospital, DaQing, Heilongjiang, 163001, China.
Department of Cardiology, DaQing Oil Field General Hospital, DaQing, Heilongjiang, 163001, China.
Environ Toxicol Pharmacol. 2016 Dec;48:110-115. doi: 10.1016/j.etap.2016.09.022. Epub 2016 Oct 3.
This work reports a one-step simple synthesis method for functionalized reduced graphene oxide (RGO) nanosheets by a Platanus orientalis leaf extract polyphenol-mediated deoxygenation of graphene oxide (GO). Microscopic and spectroscopic characterization revealed the successful deoxygenation of GO and subsequent stabilization by oxidized polyphenols of plant extract. X-ray photoelectron spectroscopy, Raman spectroscopy, and X-ray diffraction analyses were used to examine the reduction of GO. Fourier-transform infrared spectroscopy results revealed capping of RGO with oxidized polyphenols of Platanus orientalis extract, which prevented aggregation of graphene sheets. Transmission electron microscopy and atomic force microscopy images revealed the formation of thin, transparent, sheet-like graphene. The in vitro cytotoxicity of synthesized RGO exhibited a dose-dependent toxicity against cardiac cell lines of Catla catla. Further, this work opens up a green synthesis route for the development of new graphene-based technologies.
这项工作报道了一种通过悬铃木叶提取物多酚介导的氧化石墨烯（GO）脱氧反应一步简单合成功能化还原氧化石墨烯（RGO）纳米片的方法。微观和光谱表征揭示了GO的成功脱氧以及随后植物提取物氧化多酚的稳定作用。利用X射线光电子能谱、拉曼光谱和X射线衍射分析来检测GO的还原情况。傅里叶变换红外光谱结果表明悬铃木提取物的氧化多酚对RGO进行了封端，从而防止了石墨烯片的聚集。透射电子显微镜和原子力显微镜图像显示形成了薄的、透明的、片状的石墨烯。合成的RGO的体外细胞毒性对印度鲶鱼心脏细胞系表现出剂量依赖性毒性。此外，这项工作为开发新的基于石墨烯的技术开辟了一条绿色合成路线。
