Nanomedicine & Nanobiotechnology Lab, Department of Biosciences, Integral University, Kursi Road, Dasauli, Lucknow, Uttar Pradesh 226026, India.
Nanomedicine & Nanobiotechnology Lab, Department of Biosciences, Integral University, Kursi Road, Dasauli, Lucknow, Uttar Pradesh 226026, India.
Int J Antimicrob Agents. 2017 Jan;49(1):1-11. doi: 10.1016/j.ijantimicag.2016.08.016. Epub 2016 Sep 29.
Due to the appearance of antibiotic resistance and the toxicity associated with currently used antibiotics, peptide antibiotics are the need of the hour. Thus, demand for new antimicrobial agents has brought great interest in new technologies to enhance safety. One such antimicrobial molecule is bacteriocin, synthesised by various micro-organisms. Bacteriocins are widely used in agriculture, veterinary medicine as a therapeutic, and as a food preservative agent to control various infectious and food-borne pathogens. In this review, we highlight the potential therapeutic and food preservative applications of bacteriocin.
由于抗生素耐药性的出现以及目前使用的抗生素的毒性,肽类抗生素是当前的迫切需求。因此,对新型抗菌剂的需求极大地激发了新技术的发展,以提高安全性。其中一种抗菌分子是细菌素,由各种微生物合成。细菌素广泛应用于农业、兽医领域,作为一种治疗剂,也作为食品防腐剂来控制各种传染性和食源性病原体。在这篇综述中,我们强调了细菌素在治疗和食品防腐剂方面的应用潜力。