Shi Renyi, Lu Lijun, Xie Hangyu, Yan Jingwen, Xu Ting, Zhang Hua, Qi Xiaotian, Lan Yu, Lei Aiwen
College of Chemistry and Molecular Sciences, Institute for Advanced Studies (IAS), Wuhan University, Wuhan 430072, P. R. China.
School of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400030, P. R. China.
Chem Commun (Camb). 2016 Nov 3;52(90):13307-13310. doi: 10.1039/c6cc06358f.
Pd-catalyzed selective amine-oriented C8-H bond functionalization/N-dealkylative carbonylation of naphthyl amines has been achieved. The amine group from dealkylation is proposed to be the directing group for promoting this process. It represents a straightforward and easy method to access various biologically important benzo[cd]indol-2(1H)-one derivatives.
已实现钯催化的萘胺的选择性胺导向C8-H键官能化/N-脱烷基羰基化反应。脱烷基反应中产生的胺基被认为是促进该过程的导向基团。它是一种获得各种具有重要生物学意义的苯并[cd]吲哚-2(1H)-酮衍生物的直接且简便的方法。
