Kern D A, McQuade M J, Scheidt M J, Hanson B, Van Dyke T E
Periodontics Service, Fort Lee, VA.
J Periodontol. 1989 Jul;60(7):386-9. doi: 10.1902/jop.1989.60.7.386.
The purpose of this study was to assess the short and long term reduction of dentinal hypersensitivity by a single application of sodium fluoride with and without iontophoresis. Two teeth in each of 16 patients were blindly evaluated before and after treatment, and at 1, 3, and 6 months. A blast of air and tactile pressure were used to assess pain. Results indicate that there is significant, immediate reduction in dentinal hypersensitivity with the use of iontophoresis that is lost with time. The use of sodium fluoride alone had no effect. Sodium fluoride with iontophoresis was demonstrated to have an immediate post treatment effect (P less than .001) that lasted through the 3-month observation period. The data suggest that iontophoresis may be a useful adjunct to sensitivity therapy and that an immediate therapeutic effect may be achieved. The efficacy of the use of sodium fluoride alone is obscured by the natural reduction of root sensitivity observed with time.
本研究的目的是评估单次应用氟化钠（有无离子导入）对牙本质过敏症的短期和长期缓解效果。对16例患者的每例中的两颗牙齿在治疗前后以及治疗后1个月、3个月和6个月进行盲法评估。使用一阵空气和触觉压力来评估疼痛。结果表明，使用离子导入可使牙本质过敏症立即显著减轻，但这种效果会随时间消失。单独使用氟化钠没有效果。氟化钠联合离子导入在治疗后立即产生效果（P小于0.001），并持续整个3个月的观察期。数据表明，离子导入可能是一种有用的过敏症治疗辅助方法，并且可以立即产生治疗效果。随着时间推移观察到的牙根敏感性自然降低掩盖了单独使用氟化钠的疗效。
