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肝源性溃疡(其发病机制的各个方面)

[Hepatogenic ulcer (various aspects of its pathogenesis)].

作者信息

Kataev S S, Shifrin O S, Golovanova O Iu, Tsvetkova L I, Lebedev S P

出版信息

Klin Med (Mosk). 1989 Jun;67(6):32-6.

PMID:2779152
Abstract

Functional and morphological state of the stomach and duodenum was studied in 98 patients with liver cirrhosis. Hepatogenous ulcer was revealed in 21.7 per cent of the patients with alcoholic and in 25 per cent of those with viral liver cirrhosis. A specific feature of the condition was the development of ulcer in reduced gastric acid production and its asymptomatic course. The incidence of gastric and duodenal affections in liver cirrhosis was significantly higher in pronounced portal hypertension. Study of the portal blood flow with Doppler ultrasonography can reveal the risk group (patients with pronounced portal hypertension) which has high probability of the development of erosion-ulcerous lesions. These patients require obligatory medical checkups with gastric and duodenal endoscopy 2-3 times a year.

摘要

对98例肝硬化患者的胃和十二指肠的功能及形态状态进行了研究。酒精性肝硬化患者中21.7%以及病毒性肝硬化患者中25%出现肝源性溃疡。该病症的一个特点是在胃酸分泌减少的情况下溃疡形成及其无症状病程。在明显门静脉高压的情况下,肝硬化患者胃和十二指肠病变的发生率显著更高。用多普勒超声检查门静脉血流可以发现有发生糜烂性溃疡病变高概率的风险组(明显门静脉高压患者)。这些患者需要每年进行2 - 3次胃和十二指肠内镜检查的强制性医学检查。

相似文献

1
[Hepatogenic ulcer (various aspects of its pathogenesis)].肝源性溃疡(其发病机制的各个方面)
Klin Med (Mosk). 1989 Jun;67(6):32-6.
2
[Functional and morphological status of the stomach and duodenum in patients with chronic hepatitis and liver cirrhosis].[慢性肝炎和肝硬化患者胃及十二指肠的功能与形态状况]
Klin Med (Mosk). 1987 Sep;65(9):72-6.
3
Distinctive aspects of peptic ulcer disease, Dieulafoy's lesion, and Mallory-Weiss syndrome in patients with advanced alcoholic liver disease or cirrhosis.晚期酒精性肝病或肝硬化患者消化性溃疡病、Dieulafoy病变和马洛里-魏斯综合征的独特方面。
World J Gastroenterol. 2016 Jan 7;22(1):446-66. doi: 10.3748/wjg.v22.i1.446.
4
[Is there a hepatogenic ulcer? Prospective study of the incidence of peptic ulcer in portal hypertension].
Z Gastroenterol. 1987 Aug;25 Suppl 3:47-51.
5
Gastric secretion and peptic ulceration in cirrhosis.肝硬化患者的胃分泌与消化性溃疡
J Hepatol. 1993 Aug;19(1):171-82. doi: 10.1016/s0168-8278(05)80191-6.
6
[Peptic ulcer in liver cirrhosis].[肝硬化中的消化性溃疡]
Minerva Dietol Gastroenterol. 1990 Oct-Dec;36(4):223-6.
7
[Effect of liver diseases on the development of gastric secretory disorders and stomach ulcer].[肝脏疾病对胃分泌紊乱及胃溃疡发生发展的影响]
Pol Tyg Lek. 1982 Jun 28;37(19-20):577-9.
8
[Hepatogenic ulcer].肝源性溃疡
Cas Lek Cesk. 1986 May 8;125(19):577-81.
9
[Secondary gastroduodenal ulcers and erosions in patients with chronic liver and pancreatic diseases].
Vrach Delo. 1984 Oct(10):32-5.
10
Factors predisposing to peptic ulcer disease in asymptomatic cirrhotic patients.无症状肝硬化患者发生消化性溃疡疾病的 predisposing 因素。(注:这里“predisposing”原词有误,可能是“predisposing”,意为“使易患;使倾向于” ,结合语境可翻译为“相关因素” ,整句译文为“无症状肝硬化患者发生消化性溃疡疾病的相关因素。” )
Aliment Pharmacol Ther. 2005 Jun 15;21(12):1459-65. doi: 10.1111/j.1365-2036.2005.02507.x.

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