Fraser A G, Pounder R E, Burroughs A K
University Department of Medicine, Royal Free Hospital School of Medicine, London, UK.
J Hepatol. 1993 Aug;19(1):171-82. doi: 10.1016/s0168-8278(05)80191-6.
Stomach function and secretions are altered significantly in patients with cirrhosis, both with or without portal hypertension. This review covers the abnormalities of gastric acid and pepsin secretion, and gastrin release. Histological and endoscopic changes, and the impaired cytoprotection associated with cirrhosis, are discussed in the context of abnormal gastric secretion. In addition, the symptomatology and association of H. pylori, and treatment of duodenal ulceration in cirrhosis are discussed. It is clear from this review that additional studies are needed to further understand gastric function in cirrhotic patients.
无论有无门静脉高压，肝硬化患者的胃功能和分泌物都会发生显著改变。本综述涵盖胃酸和胃蛋白酶分泌以及胃泌素释放的异常情况。在胃分泌异常的背景下，讨论了组织学和内镜检查的变化以及与肝硬化相关的细胞保护受损情况。此外，还讨论了幽门螺杆菌的症状学、关联情况以及肝硬化患者十二指肠溃疡的治疗。从本综述可以清楚地看出，需要进一步开展研究以深入了解肝硬化患者的胃功能。
