Louhelainen Jari
Pharmacy and Biomolecular Sciences, Liverpool John Moores University, James Parsons Building, Byrom Street, Liverpool L3 3AF, UK.
Microarrays (Basel). 2016 Oct 25;5(4):27. doi: 10.3390/microarrays5040027.
The papers published in this Special Issue "SNP arrays" (Single Nucleotide Polymorphism Arrays) focus on several perspectives associated with arrays of this type. The range of papers vary from a case report to reviews, thereby targeting wider audiences working in this field. The research focus of SNP arrays is often human cancers but this Issue expands that focus to include areas such as rare conditions, animal breeding and bioinformatics tools. Given the limited scope, the spectrum of papers is nothing short of remarkable and even from a technical point of view these papers will contribute to the field at a general level. Three of the papers published in this Special Issue focus on the use of various SNP array approaches in the analysis of three different cancer types. Two of the papers concentrate on two very different rare conditions, applying the SNP arrays slightly differently. Finally, two other papers evaluate the use of the SNP arrays in the context of genetic analysis of livestock. The findings reported in these papers help to close gaps in the current literature and also to give guidelines for future applications of SNP arrays.
本期特刊“单核苷酸多态性阵列”发表的论文聚焦于与这类阵列相关的多个视角。论文范围从病例报告到综述，从而面向该领域更广泛的受众。单核苷酸多态性阵列的研究重点通常是人类癌症，但本期将这一重点扩展到包括罕见病、动物育种和生物信息学工具等领域。鉴于篇幅有限，论文的范围相当可观，而且即使从技术角度来看，这些论文也将在总体层面上为该领域做出贡献。本期特刊发表的三篇论文聚焦于使用各种单核苷酸多态性阵列方法分析三种不同类型的癌症。其中两篇论文专注于两种截然不同的罕见病，对单核苷酸多态性阵列的应用略有不同。最后，另外两篇论文评估了单核苷酸多态性阵列在牲畜遗传分析中的应用。这些论文中报告的研究结果有助于填补当前文献中的空白，并为单核苷酸多态性阵列的未来应用提供指导。
