Bialystok University of Technology, Division of Chemistry, Wiejska 45E, 15-351 Bialystok, Poland.
Bialystok University of Technology, Division of Chemistry, Wiejska 45E, 15-351 Bialystok, Poland.
Spectrochim Acta A Mol Biomol Spectrosc. 2017 Feb 15;173:757-771. doi: 10.1016/j.saa.2016.10.031. Epub 2016 Oct 19.
Flavonols with varied hydroxyl substitution can act as strong antioxidants. Thanks to their ability to chelate metals as well as to donate hydrogen atoms they have capacity to scavenge free radicals. Their metal complexes are often more active in comparison with free ligands. They exhibit interesting biological properties, e.g. anticancer, antiphlogistic and antibacterial. The relationship between molecular structure and their biological properties was intensively studied using spectroscopic methods (UV-Vis, IR, Raman, NMR, ESI-MS). The aim of this paper is review on spectroscopic analyses of molecular structure and biological activity of hydroxyflavonol metal complexes.
具有不同羟基取代的类黄酮可以作为强抗氧化剂。由于它们能够螯合金属以及提供氢原子，因此具有清除自由基的能力。与游离配体相比，它们的金属配合物通常更具活性。它们表现出有趣的生物特性，例如抗癌、抗炎和抗菌。使用光谱方法（UV-Vis、IR、Raman、NMR、ESI-MS）对分子结构与其生物特性之间的关系进行了深入研究。本文的目的是综述羟基黄酮金属配合物的分子结构和生物活性的光谱分析。
