Gladyshev Timothy V, Gladyshev Vadim N
University of Massachusetts, Amherst, MA 01002, USA.
Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Trends Mol Med. 2016 Dec;22(12):995-996. doi: 10.1016/j.molmed.2016.09.009. Epub 2016 Oct 25.
The debate on the relationship between aging and disease is centered on whether aging is a normal/natural/physiological process or it represents a pathology. Considering this relationship from medical, molecular, social, and historical perspectives, we argue that aging is neither a disease, nor a non-disease. Instead, it combines all age-related diseases and their preclinical forms, in addition to other pathological changes.
关于衰老与疾病关系的争论集中在衰老究竟是一个正常/自然/生理过程,还是代表一种病理状态。从医学、分子、社会和历史角度审视这种关系,我们认为衰老既不是一种疾病,也不是非疾病状态。相反,除了其他病理变化外,它还包含了所有与年龄相关的疾病及其临床前形式。