Parkpinyo Nichamon, Inthasorn Perapong, Laiwejpithaya Somsak, Punnarat Tippawan
Department of Obstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand E-mail :
Asian Pac J Cancer Prev. 2016;17(9):4457-4461.
To determine the prevalence of abnormal cervical cytology, as diagnosed using a liquid-based cytology technique, in pregnant women attending the Antenatal Care (ANC) clinic at Siriraj Hospital.
This cross-sectional study included 655 first-visit pregnant women who attended ANC clinic at Siriraj Hospital during June to November 2015 study period. After receiving routine antenatal care, cervical cytology screening was performed with the Siriraj liquid-based cytology technique. All specimens were reviewed by a certi ed cytopathologist using Bethesda System 2001 criteria. Patients with abnormal PAP results characterized as epithelial cell abnormalities were referred to a gynecologic oncologist for further management according to ASCCP Guidelines 2012.
Mean age of participants was 28.9±6.2 years. Prevalence of abnormal cervical cytology was 3.4% (95% CI: 2.0-4.7). Among this group, there were ASC-US, ASC-H, LSIL, HSIL for 12(1.8%), 2(0.3%), 7(1.1%) and 1(0.2%), respectively. In 633 specimens of the normal group, infection was identified in 158 specimens (24.1%) which were caused by Candida spp. and Trichomonas vaginalis. Regarding patient perception about the importance of cervical cancer screening, although most women perceived screening to be important, 54% of participants had never been screened for cervical cancer. Rate of loss to follow-up in the postpartum period was as high as 41.8%.
Prevalence of abnormal cervical cytology in pregnant women attending the ANC clinic at Siriraj Hospital was 3.4%. Inclusion of cervical cancer screening as part of antenatal assessment can help to identify precancerous lesions or cervical cancers in patients who might otherwise not be screened, thereby facilitating early treatment and improved patient outcomes.
确定在诗里拉吉医院产前保健（ANC）门诊就诊的孕妇中，采用液基细胞学技术诊断的宫颈细胞学异常的患病率。
这项横断面研究纳入了2015年6月至11月研究期间在诗里拉吉医院ANC门诊就诊的655名初诊孕妇。在接受常规产前检查后，采用诗里拉吉液基细胞学技术进行宫颈细胞学筛查。所有标本均由一名认证的细胞病理学家根据2001年贝塞斯达系统标准进行复查。根据2012年美国阴道镜及宫颈病理学会（ASCCP）指南，将巴氏涂片结果异常且表现为上皮细胞异常的患者转诊给妇科肿瘤学家进行进一步处理。
参与者的平均年龄为28.9±6.2岁。宫颈细胞学异常的患病率为3.4%（95%置信区间：2.0 - 4.7）。在该组中，非典型鳞状细胞不能明确意义（ASC-US）、非典型鳞状细胞不排除高度病变（ASC-H）、低度鳞状上皮内病变（LSIL）、高度鳞状上皮内病变（HSIL）分别有12例（1.8%）、2例（0.3%）、7例（1.1%）和1例（0.2%）。在正常组的633份标本中，158份标本（24.1%）检测到感染，感染由念珠菌属和阴道毛滴虫引起。关于患者对宫颈癌筛查重要性的认知，尽管大多数女性认为筛查很重要，但54%的参与者从未接受过宫颈癌筛查。产后失访率高达41.8%。
在诗里拉吉医院ANC门诊就诊的孕妇中，宫颈细胞学异常的患病率为3.4%。将宫颈癌筛查纳入产前评估的一部分，有助于识别那些可能未接受筛查的患者中的癌前病变或宫颈癌，从而促进早期治疗并改善患者预后。
