Valente Nicoletta, Lupi Silvia, Stefanati Armando, Cova Marisa, Sulcaj Najada, Piccinni Lucia, Gabutti Giovanni
Department of Medical Sciences, University of Ferrara, Ferrara, Italy.
Department of Public Health, Ferrara Local Health Authority, Ferrara, Italy.
BMJ Open. 2016 Oct 18;6(10):e011539. doi: 10.1136/bmjopen-2016-011539.
The aim of the study was to evaluate awareness of the varicella zoster virus and the acceptability of the newly available herpes zoster (HZ) vaccine in the over 50 years old general population.
The research was observational.
The study was carried out in Ferrara by administering a questionnaire to patients of the Local Health Authority (LHA), general practitioners (GPs) and Public Health Department outpatient clinics.
The questionnaire was completed by 1001 residents of Ferrara Province.
Of the respondents, 98% and 95% (57% female) were aware of varicella and HZ, respectively, but 91% were unaware of the HZ vaccine. Nevertheless, 58% declared that they were in favour of vaccination in this regard, and the acceptability of the vaccine was positively affected by: age (p=0.005); knowing someone who had suffered from HZ (p=0.05); being in favour of vaccination in general (p<0.0001); receiving advice to do so from their GP (p<0.0001) and willingness to get vaccinated even on a fee-paying basis (p<0.0001). Indeed, most (73%) respondents were willing to pay to get vaccinated, indicating an ideal cost of €50. Higher education (p=0.04), being in favour of vaccinations in general (p<0.0001) and GP advice (p<0.0001) positively affected this choice. Furthermore, 61% of the participants initially unfavourable (p<0.0001) to this immunisation would change their decision not to vaccinate thanks to their GP's advice.
This study assessed the level of awareness and the attitudes of the population aged over 50 years, highlighting aspects to be focused on in the promotion of the HZ vaccine.
本研究旨在评估50岁以上普通人群对水痘带状疱疹病毒的认知以及对新上市的带状疱疹（HZ）疫苗的接受程度。
本研究为观察性研究。
该研究在费拉拉进行，通过向当地卫生当局（LHA）的患者、全科医生（GPs）和公共卫生部门门诊发放问卷来开展。
费拉拉省的1001名居民完成了问卷。
在受访者中，分别有98%和95%（57%为女性）知晓水痘和HZ，但91%不知道HZ疫苗。然而，58%表示他们赞成在这方面进行疫苗接种，疫苗的可接受性受到以下因素的积极影响：年龄（p = 0.005）；认识患过HZ的人（p = 0.05）；总体上赞成接种疫苗（p < 0.0001）；从全科医生处得到接种建议（p < 0.0001）以及即使付费也愿意接种疫苗（p < 0.0001）。实际上，大多数（73%）受访者愿意付费接种疫苗，理想费用为50欧元。高等教育程度（p = 0.04）、总体上赞成接种疫苗（p < 0.0001）和全科医生的建议（p < 0.0001）对这一选择有积极影响。此外，61%最初不赞成（p < 0.0001）这种免疫接种的参与者会因全科医生的建议而改变不接种的决定。
本研究评估了50岁以上人群的认知水平和态度，突出了在推广HZ疫苗时应关注的方面。
