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早期干预精神病服务的经济影响:来自英国一项纵向回顾性对照研究的结果。

Economic impact of early intervention in psychosis services: results from a longitudinal retrospective controlled study in England.

作者信息

Tsiachristas Apostolos, Thomas Tony, Leal Jose, Lennox Belinda R

机构信息

Health Economics Research Centre, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

Janssen Healthcare Innovation, Johnson & Johnson, High Wycombe, UK.

出版信息

BMJ Open. 2016 Oct 20;6(10):e012611. doi: 10.1136/bmjopen-2016-012611.

Abstract

OBJECTIVES

To demonstrate the costs, outcomes and economic impact of early intervention in psychosis (EIP) services.

DESIGN

Longitudinal retrospective observational study of service usage and outcome data from mental health and acute care services for all those with a diagnosis of psychosis in contact with mental health services over a 3-year period (April 2010-March 2013).

SETTING

Thames Valley and South Midlands region in England (region covered by Oxford Academic Health Science Network).

PARTICIPANTS

3674 people with psychosis, aged 16-35 years.

INTERVENTIONS

EIP team or other community mental health teams.

MAIN OUTCOME MEASURES

Change in housing status, change in employment status and improvement on each of the four domains of the Health of the Nation Outcome Scale (HONOS) questionnaire. Costs of mental and acute health inpatient, outpatient and community service use were also included in the study.

RESULTS

Patients in EIP services were 116% more likely (95% CI 1.263 to 3.708) to gain employment, 52% more likely to become accommodated in a mainstream house (95% CI 0.988 to 2.326) and 17% more likely to have an improvement in the emotional well-being domain of the HONOS questionnaire (95% CI 1.067 to 1.285), as compared to those in non-EIP services. Annual National Health Service (NHS) costs were also significantly lower for patients using EIP services compared to non-users. The mean annual NHS cost savings associated with EIP were £4031 (95% CI £1281 to £6780). These mostly came from lower mental health inpatient costs (£4075, 95% CI £1164 to £6986), lower acute hospital outpatient costs (£59, 95% CI £9 to £109), lower accident and emergency costs (£31, 95% CI £12 to £51), and higher mental health community costs (£648, 95% CI £122 to £1175). If all people with a first-episode psychosis across England were to be treated by EIP services, the savings in societal costs would be an estimated £63.3 million per year, of which £33.5 million would be in NHS costs.

CONCLUSIONS

Treatment within an EIP service is associated with better health and social outcomes, and reduced costs.

摘要

目的

证明精神病早期干预(EIP)服务的成本、结果及经济影响。

设计

对2010年4月至2013年3月这3年期间与心理健康服务机构接触的所有确诊精神病患者的心理健康及急症护理服务使用情况和结果数据进行纵向回顾性观察研究。

地点

英国泰晤士河谷和南米德兰兹地区(牛津学术健康科学网络覆盖地区)。

参与者

3674名年龄在16至35岁之间的精神病患者。

干预措施

EIP团队或其他社区心理健康团队。

主要结局指标

住房状况变化、就业状况变化以及《国民健康状况量表》(HONOS)问卷四个领域中每个领域的改善情况。研究还纳入了心理健康及急症住院、门诊和社区服务使用的成本。

结果

与非EIP服务的患者相比,接受EIP服务的患者就业可能性高116%(95%置信区间为1.263至3.708),入住主流住房的可能性高52%(95%置信区间为0.988至2.326),HONOS问卷情感幸福领域改善的可能性高17%(95%置信区间为1.067至1.285)。与非使用者相比,使用EIP服务的患者每年的国民医疗服务体系(NHS)成本也显著更低。与EIP相关的平均每年NHS成本节省为4031英镑(95%置信区间为1281英镑至6780英镑)。这些节省大多来自较低的心理健康住院成本(4075英镑,95%置信区间为1164英镑至6986英镑)、较低的急症医院门诊成本(59英镑,95%置信区间为9英镑至109英镑)、较低的事故及急诊成本(31英镑,95%置信区间为12英镑至51英镑)以及较高的心理健康社区成本(648英镑,95%置信区间为122英镑至1175英镑)。如果英格兰所有首次发作精神病患者都接受EIP服务治疗,社会成本每年将节省约6330万英镑,其中3350万英镑为NHS成本。

结论

EIP服务内的治疗与更好的健康和社会结果以及成本降低相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce95/5073534/4a37c4f6965d/bmjopen2016012611f01.jpg

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