O'Callaghan-Gordo Cristina, Casabonne Delphine, Carrilho Carla, Ferro Josefo, Lorenzoni Cesaltina, Zaqueu Clesio, Nhabomba Augusto, Aguilar Ruth, Bassat Quique, de Sanjosé Sílvia, Dobaño Carlota, Kogevinas Manolis
ISGlobal, Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain.
Universitat Pompeu Fabra (UPF), Barcelona, Spain.
Am J Trop Med Hyg. 2016 Dec 7;95(6):1459-1462. doi: 10.4269/ajtmh.16-0424. Epub 2016 Oct 31.
Data on the burden and incidence of endemic Burkitt lymphoma (eBL) across Mozambique are scarce. We retrospectively retrieved information on eBL cases from reports of the three main hospitals of Mozambique: Maputo Central Hospital (MCH), Beira Central Hospital (BCH), and Nampula Central Hospital (NCH) between 2004 and 2014. For 2015, we prospectively collected information of new eBL cases attending these hospitals. A total of 512 eBL cases were reported between 2004 and 2015: 153 eBL cases were reported in MCH, 195 in BCH, and 164 in NCH. Mean age of cases was 6.9 years (standard deviation = 2.8); 63% (319/504) of cases were males. For 2015, the estimated incidence rate of eBL was 2.0, 1.7, and 3.9 per 10 person-year at risk in MCH, BCH, and NCH, respectively. Incidence was higher in NCH (northern Mozambique), where intensity of malaria transmission is higher. Data presented show that eBL is a common pediatric malignancy in Mozambique, as observed in neighboring countries.
关于莫桑比克全国地方性伯基特淋巴瘤（eBL）的负担和发病率的数据十分匮乏。我们回顾性地从莫桑比克三家主要医院的报告中检索了eBL病例信息：马普托中心医院（MCH）、贝拉中心医院（BCH）和楠普拉中心医院（NCH）在2004年至2014年期间的病例信息。对于2015年，我们前瞻性地收集了到这些医院就诊的新发eBL病例信息。2004年至2015年期间共报告了512例eBL病例：MCH报告了153例eBL病例，BCH报告了195例，NCH报告了164例。病例的平均年龄为6.9岁（标准差 = 2.8）；63%（319/504）的病例为男性。2015年，MCH、BCH和NCH的eBL估计发病率分别为每10人年发病2.0例、1.7例和3.9例。发病率在NCH（莫桑比克北部）较高，那里疟疾传播强度更高。所呈现的数据表明，正如在邻国所观察到的那样，eBL在莫桑比克是一种常见的儿童恶性肿瘤。
